C
Christopher J. Frederickson
Researcher at University of Texas Medical Branch
Publications - 99
Citations - 12617
Christopher J. Frederickson is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Zinc & Hippocampal formation. The author has an hindex of 48, co-authored 97 publications receiving 12082 citations. Previous affiliations of Christopher J. Frederickson include Massachusetts Institute of Technology & University of Texas at Dallas.
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Journal ArticleDOI
Zinc-containing afferent projections to the rat corticomedial amygdaloid complex: a retrograde tracing study.
TL;DR: The present work describes the origins of one major component of the zinc‐containing innervation of the amygdaloid complex, namely, the component that innervates the corticomedial complex.
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Imaging zinc: old and new tools.
TL;DR: The zinc-imaging tools, from dithizonate to the newest FRET-based sensors, that have galvanized biomedical science are covered in this Perspective.
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Zinc-secreting Paneth cells studied by ZP fluorescence.
Leonard J. Giblin,Christopher J. Chang,Anthony F. Bentley,Cathleen J. Frederickson,Stephen J. Lippard,Christopher J. Frederickson +5 more
TL;DR: It is shown that zinc is coreleased with other Paneth cell anti-microbials, and that the intact intestine is necessary for secretion into the crypt lumen, suggesting that this ionic zinc pool is secreted under physiological conditions.
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Protective effects of zinc chelation in traumatic brain injury correlate with upregulation of neuroprotective genes in rat brain.
Helen L. Hellmich,Christopher J. Frederickson,Douglas S. DeWitt,Ricardo Saban,Margaret Parsley,Rachael T. Stephenson,Marco A. De Velasco,Tatsuo Uchida,Megumi Shimamura,Megumi Shimamura,Donald S. Prough +10 more
TL;DR: Zinc chelation induced the expression of several neuroprotective genes; neuroprot protective gene expression correlated with substantially decreased numbers of TUNEL-positive cells.
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Clioquinol effects on tissue chelatable zinc in mice.
Yuval B. Nitzan,Israel Sekler,Christopher J. Frederickson,Douglas A. Coulter,Rengarajan V. Balaji,Shu-Ling Liang,Ariel Margulis,Michal Hershfinkel,William F. Silverman +8 more
TL;DR: The findings suggest that CQ administered orally to patients with Alzheimer's disease should not significantly perturb chelatable zinc levels in key organs and may be used over long periods without adverse endocrinological and reproductive effects related to zinc deficiency.