C
Christopher J. Frederickson
Researcher at University of Texas Medical Branch
Publications - 99
Citations - 12617
Christopher J. Frederickson is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Zinc & Hippocampal formation. The author has an hindex of 48, co-authored 97 publications receiving 12082 citations. Previous affiliations of Christopher J. Frederickson include Massachusetts Institute of Technology & University of Texas at Dallas.
Papers
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Journal ArticleDOI
Evidence That the ZNT3 Protein Controls the Total Amount of Elemental Zinc in Synaptic Vesicles
David H. Linkous,Jane M. Flinn,Jae Y. Koh,Antonio Lanzirotti,Antonio Lanzirotti,Paul M. Bertsch,Blair F. Jones,Leonard J. Giblin,Christopher J. Frederickson +8 more
TL;DR: A novel technique, microprobe synchrotron X-ray fluorescence, reveals that the normal 2- to 3-fold elevation of zinc concentration normally present in the hippocampal mossy fibers is absent in Slc30a3 knockout (ZNT3) mice, confirming the metal-transporting role of the ZNT3 protein in the brain.
Journal ArticleDOI
Labeling of the neurons of origin of zinc-containing pathways by intraperitoneal injections of sodium selenite
TL;DR: It is presented evidence, in the rat, that zinc-selenium precipitates formed in vivo after intraperitoneal injections of sodium selenite are translocated by colchicine-sensitive retrograde transport to neural perikarya when animals are allowed to survive 12-24 h after the selenites administration.
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Distribution of histochemically reactive zinc in the forebrain of the rat.
TL;DR: The major cytoarchitectonic regions of the rat brain that stain with the Timm-Danscher metal stain were tested with the fluorescent probe for zinc, 6-methoxy 8-para toluene sulfonamide quinoline (TSQ), and it was concluded that theTimm- Danscher staining generally indicates zinc-containing axonal boutons.
Patent
Making apparatus for conducting biochemical analyses
TL;DR: In this paper, a self-contained apparatus for conducting bio-chemical reactions and analyses is formed in a compact structure made from a substrate which includes a plurality of reaction chambers and a pluralityof analysis chambers which are in fluid communication with the reaction chambers.
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Raphe unit activity in freely moving cats: Effects of benzodiazepines
TL;DR: Raphe unit activity remained suppressed during phasic increases in EMG activity during eating, grooming, or predatory behavior, suggesting that benzodiazepines also have a direct inhibitory action on raphe cells.