C
Christopher M. Rembold
Researcher at University of Virginia
Publications - 103
Citations - 4846
Christopher M. Rembold is an academic researcher from University of Virginia. The author has contributed to research in topics: Myosin & Phosphorylation. The author has an hindex of 37, co-authored 103 publications receiving 4584 citations. Previous affiliations of Christopher M. Rembold include Mayo Clinic & University of Virginia Health System.
Papers
More filters
Journal ArticleDOI
Common Carotid Intima-Media Thickness Measurements in Cardiovascular Risk Prediction A Meta-analysis
Hester M. den Ruijter,Sanne A.E. Peters,Todd J. Anderson,Annie Britton,Jacqueline M. Dekker,Marinus J.C. Eijkemans,Gunnar Engström,Gregory W. Evans,Jacqueline de Graaf,Diederick E. Grobbee,Diederick E. Grobbee,Bo Hedblad,Albert Hofman,Suzanne Holewijn,Ai Ikeda,Maryam Kavousi,Kazuo Kitagawa,Akihiko Kitamura,Hendrik Koffijberg,Eva Lonn,Matthias W. Lorenz,Ellisiv B. Mathiesen,Giel Nijpels,Shuhei Okazaki,Daniel H. O'Leary,Joseph F. Polak,Jackie F. Price,Christine Robertson,Christopher M. Rembold,Maria Rosvall,Tatjana Rundek,Jukka T. Salonen,Matthias Sitzer,Coen D.A. Stehouwer,Jacqueline C.M. Witteman,Karel G.M. Moons,Michiel L. Bots +36 more
TL;DR: The addition of common CIMT measurements to the Framingham Risk Score was associated with small improvement in 10-year risk prediction of first-time myocardial infarction or stroke, but this improvement is unlikely to be of clinical importance.
Journal ArticleDOI
Number needed to screen: development of a statistic for disease screening
TL;DR: Of the screening strategies evaluated, screening for, and treatment of, dyslipidaemia and hypertension seem to produce the largest clinical benefit.
Journal ArticleDOI
Growth of the human heart relative to body surface area.
TL;DR: This study indicates that intracardiac areas may be indexed for body surface area, but that linear dimensions and volumes have a nonlinear relation to surface area and are more appropriately indexed by surface area to the 0.5 and 1.5 power level.
Journal ArticleDOI
Myoplasmic [Ca2+] determines myosin phosphorylation in agonist-stimulated swine arterial smooth muscle.
TL;DR: The relation between phosphorylation and Vo or steady-state stress was invariant with all tested stimuli, suggesting that Ca2+-dependent crossbridge phosphorylated is the primary determinant of the mechanical response.
Journal ArticleDOI
Regulation of contraction and relaxation in arterial smooth muscle
TL;DR: There are two proposed mechanisms for changes in the [Ca2+]i sensitivity of phosphorylation: Ca(2+)-dependent decreases in the [*Ca2-i]i sensitive to myosin light chain kinase by Ca( 2+)-calmodulin protein kinase II and agonist-dependent increases in the[Ca2+) sensitivity ofosphorylation by inhibition of a myosIn light chain phosphatase.