H
Hester M. den Ruijter
Researcher at Utrecht University
Publications - 189
Citations - 12585
Hester M. den Ruijter is an academic researcher from Utrecht University. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 38, co-authored 159 publications receiving 10571 citations. Previous affiliations of Hester M. den Ruijter include University of Amsterdam.
Papers
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Genetic studies of body mass index yield new insights for obesity biology
Adam E. Locke,Bratati Kahali,Sonja I. Berndt,Anne E. Justice,Tune H. Pers,Felix R. Day,Corey Powell,Sailaja Vedantam,Martin L. Buchkovich,Jian Yang,Damien C. Croteau-Chonka,Tõnu Esko,Tove Fall,Teresa Ferreira,Stefan Gustafsson,Zoltán Kutalik,Jian'an Luan,Reedik Mägi,Joshua C. Randall,Thomas W. Winkler,Andrew R. Wood,Tsegaselassie Workalemahu,Jessica D. Faul,Jennifer A. Smith,Jing Hua Zhao,Wei Zhao,Jin Chen,Rudolf S N Fehrmann,Åsa K. Hedman,Juha Karjalainen,Ellen M. Schmidt,Devin Absher,Najaf Amin,Denise Anderson,Marian Beekman,Jennifer L. Bolton,Jennifer L. Bragg-Gresham,Steven Buyske,Ayse Demirkan,Guohong Deng,Georg Ehret,Bjarke Feenstra,Mary F. Feitosa,Krista Fischer,Anuj Goel,Jian Gong,Anne U. Jackson,Stavroula Kanoni,Marcus E. Kleber,Kati Kristiansson,Unhee Lim,Vaneet Lotay,Massimo Mangino,Irene Mateo Leach,Carolina Medina-Gomez,Sarah E. Medland,Mike A. Nalls,Cameron D. Palmer,Dorota Pasko,Sonali Pechlivanis,Marjolein Peters,Inga Prokopenko,Dmitry Shungin,Alena Stančáková,Rona J. Strawbridge,Yun Ju Sung,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sander W. van der Laan,Jessica van Setten,Jana V. van Vliet-Ostaptchouk,Zhaoming Wang,Loic Yengo,Weihua Zhang,Aaron Isaacs,Eva Albrecht,Johan Ärnlöv,Gillian M. Arscott,Antony P. Attwood,Stefania Bandinelli,Amy Barrett,Isabelita Bas,Claire Bellis,Amanda J. Bennett,Christian Berne,Roza Blagieva,Matthias Blüher,Stefan Böhringer,Lori L. Bonnycastle,Yvonne Böttcher,Heather A. Boyd,Marcel Bruinenberg,Ida Henriette Caspersen,Yii-Der Ida Chen,Robert Clarke,E. Warwick Daw,Anton J. M. de Craen,Graciela E. Delgado,Maria Dimitriou,Alex S. F. Doney,Niina Eklund,Karol Estrada,Elodie Eury,Lasse Folkersen,Ross M. Fraser,Melissa E. Garcia,Frank Geller,Vilmantas Giedraitis,Bruna Gigante,Alan S. Go,Alain Golay,Alison H. Goodall,Scott D. Gordon,Mathias Gorski,Hans-Jörgen Grabe,Harald Grallert,Tanja B. Grammer,Jürgen Gräßler,Henrik Grönberg,Christopher J. Groves,Gaëlle Gusto,Jeffrey Haessler,Per Hall,Toomas Haller,Göran Hallmans,Catharina A. Hartman,Maija Hassinen,Caroline Hayward,Nancy L. Heard-Costa,Quinta Helmer,Christian Hengstenberg,Oddgeir L. Holmen,Jouke-Jan Hottenga,Alan James,Janina M. Jeff,Åsa Johansson,Jennifer Jolley,Thorhildur Juliusdottir,Leena Kinnunen,Wolfgang Koenig,Markku Koskenvuo,Wolfgang Kratzer,Jaana Laitinen,Claudia Lamina,Karin Leander,Nanette R. Lee,Peter Lichtner,Lars Lind,Jaana Lindström,Ken Sin Lo,Stéphane Lobbens,Roberto Lorbeer,Yingchang Lu,François Mach,Patrik K. E. Magnusson,Anubha Mahajan,Wendy L. McArdle,Stela McLachlan,Cristina Menni,Sigrun Merger,Evelin Mihailov,Lili Milani,Alireza Moayyeri,Keri L. Monda,Mario A. Morken,Antonella Mulas,Gabriele Müller,Martina Müller-Nurasyid,Arthur W. Musk,Ramaiah Nagaraja,Markus M. Nöthen,Ilja M. Nolte,Stefan Pilz,Nigel W. Rayner,Frida Renström,Rainer Rettig,Janina S. Ried,Stephan Ripke,Neil R. Robertson,Lynda M. Rose,Serena Sanna,Hubert Scharnagl,Salome Scholtens,Fredrick R. Schumacher,William R. Scott,Thomas Seufferlein,Jianxin Shi,Albert V. Smith,Joanna Smolonska,Alice Stanton,Valgerdur Steinthorsdottir,Kathleen Stirrups,Heather M. Stringham,Johan Sundström,Morris A. Swertz,Amy J. Swift,Ann-Christine Syvänen,Sian-Tsung Tan,Bamidele O. Tayo,Barbara Thorand,Gudmar Thorleifsson,Jonathan Tyrer,Hae-Won Uh,Liesbeth Vandenput,Frank C. Verhulst,Sita H. Vermeulen,Niek Verweij,Judith M. Vonk,Lindsay L. Waite,Helen R. Warren,Dawn M. Waterworth,Michael N. Weedon,Lynne R. Wilkens,Christina Willenborg,Tom Wilsgaard,Mary K. Wojczynski,Andrew Wong,Alan F. Wright,Qunyuan Zhang,Eoin P. Brennan,Murim Choi,Zari Dastani,Alexander W. Drong,Per Eriksson,Anders Franco-Cereceda,Jesper R. Gådin,Ali G. Gharavi,Michael E. Goddard,Robert E. Handsaker,Jinyan Huang,Fredrik Karpe,Sekar Kathiresan,Sarah Keildson,Krzysztof Kiryluk,Michiaki Kubo,Jong-Young Lee,Liming Liang,Richard P. Lifton,Baoshan Ma,Steven A. McCarroll,Amy Jayne McKnight,Josine L. Min,Miriam F. Moffatt,Grant W. Montgomery,Joanne M. Murabito,George Nicholson,Dale R. Nyholt,Yukinori Okada,John R. B. Perry,Rajkumar Dorajoo,Eva Reinmaa,Rany M. Salem,Niina Sandholm,Robert A. Scott,Lisette Stolk,Atsushi Takahashi,Toshihiro Tanaka,Ferdinand M. van't Hooft,Anna A. E. Vinkhuyzen,Harm-Jan Westra,Wei Zheng,Krina T. Zondervan,Andrew C. Heath,Dominique Arveiler,Stephan J. L. Bakker,John Beilby,Richard N. Bergman,John Blangero,Pascal Bovet,Harry Campbell,Mark J. Caulfield,Giancarlo Cesana,Aravinda Chakravarti,Daniel I. Chasman,Peter S. Chines,Francis S. Collins,Dana C. Crawford,L. Adrienne Cupples,Daniele Cusi,John Danesh,Ulf de Faire,Hester M. den Ruijter,Anna F. Dominiczak,Raimund Erbel,Jeanette Erdmann,Johan G. Eriksson,Martin Farrall,Stephan B. Felix,Ele Ferrannini,Jean Ferrières,Ian Ford,Nita G. Forouhi,Terrence Forrester,Oscar H. Franco,Ron T. Gansevoort,Pablo V. Gejman,Christian Gieger,Omri Gottesman,Vilmundur Gudnason,Ulf Gyllensten,Alistair S. Hall,Tamara B. Harris,Andrew T. Hattersley,Andrew A. Hicks,Lucia A. Hindorff,Aroon D. Hingorani,Albert Hofman,Georg Homuth,G. Kees Hovingh,Steve E. Humphries,Steven C. Hunt,Elina Hyppönen,Thomas Illig,Kevin B. Jacobs,Marjo-Riitta Järvelin,Karl-Heinz Jöckel,Berit Johansen,Pekka Jousilahti,J. Wouter Jukema,Antti Jula,Jaakko Kaprio,John J.P. Kastelein,Sirkka Keinänen-Kiukaanniemi,Lambertus A. Kiemeney,Paul Knekt,Jaspal S. Kooner,Charles Kooperberg,Peter Kovacs,Aldi T. Kraja,Meena Kumari,Johanna Kuusisto,Timo A. Lakka,Claudia Langenberg,Loic Le Marchand,Terho Lehtimäki,Valeriya Lyssenko,Satu Männistö,André Marette,Tara C. Matise,Colin A. McKenzie,Barbara McKnight,Frans L. Moll,Andrew D. Morris,Andrew P. Morris,Jeffrey C. Murray,Mari Nelis,Claes Ohlsson,Albertine J. Oldehinkel,Ken K. Ong,Pamela A. F. Madden,Gerard Pasterkamp,John F. Peden,Annette Peters,Dirkje S. Postma,Peter P. Pramstaller,Jackie F. Price,Lu Qi,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Treva Rice,Paul M. Ridker,John D. Rioux,Marylyn D. Ritchie,Igor Rudan,Veikko Salomaa,Nilesh J. Samani,Jouko Saramies,Mark A. Sarzynski,Heribert Schunkert,Peter Schwarz,Peter S. Sever,Alan R. Shuldiner,Juha Sinisalo,Ronald P. Stolk,Konstantin Strauch,Anke Tönjes,David-Alexandre Trégouët,Angelo Tremblay,Elena Tremoli,Jarmo Virtamo,Marie-Claude Vohl,Uwe Völker,Gérard Waeber,Gonneke Willemsen,Jacqueline C. M. Witteman,M. Carola Zillikens,Linda S. Adair,Philippe Amouyel,Folkert W. Asselbergs,Themistocles L. Assimes,Murielle Bochud,Bernhard O. Boehm,Eric Boerwinkle,Stefan R. Bornstein,Erwin P. Bottinger,Claude Bouchard,Stéphane Cauchi,John C. Chambers,Stephen J. Chanock,Richard S. Cooper,Paul I.W. de Bakker,George Dedoussis,Luigi Ferrucci,Paul W. Franks,Philippe Froguel,Leif Groop,Christopher A. Haiman,Anders Hamsten,Jennie Hui,David J. Hunter,Kristian Hveem,Robert C. Kaplan,Mika Kivimäki,Diana Kuh,Markku Laakso,Yongmei Liu,Nicholas G. Martin,Winfried März,Mads Melbye,Andres Metspalu,Susanne Moebus,Patricia B. Munroe,Inger Njølstad,Ben A. Oostra,Colin N. A. Palmer,Nancy L. Pedersen,Markus Perola,Louis Pérusse,Ulrike Peters,Chris Power,Thomas Quertermous,Rainer Rauramaa,Fernando Rivadeneira,Timo Saaristo,Danish Saleheen,Naveed Sattar,Eric E. Schadt,David Schlessinger,P. Eline Slagboom,Harold Snieder,Tim D. Spector,Unnur Thorsteinsdottir,Michael Stumvoll,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,Pim van der Harst,Mark Walker,Henri Wallaschofski,Nicholas J. Wareham,Hugh Watkins,David R. Weir,H-Erich Wichmann,James F. Wilson,Pieter Zanen,Ingrid B. Borecki,Panos Deloukas,Caroline S. Fox,Iris M. Heid,Jeffrey R. O'Connell,David P. Strachan,Kari Stefansson,Cornelia M. van Duijn,Gonçalo R. Abecasis,Lude Franke,Timothy M. Frayling,Mark I. McCarthy,Peter M. Visscher,André Scherag,Cristen J. Willer,Michael Boehnke,Karen L. Mohlke,Cecilia M. Lindgren,Jacques S. Beckmann,Inês Barroso,Kari E. North,Erik Ingelsson,Joel N. Hirschhorn,Ruth J. F. Loos,Elizabeth K. Speliotes +481 more
TL;DR: This paper conducted a genome-wide association study and meta-analysis of body mass index (BMI), a measure commonly used to define obesity and assess adiposity, in up to 339,224 individuals.
Journal ArticleDOI
Defining the role of common variation in the genomic and biological architecture of adult human height
Andrew R. Wood,Tõnu Esko,Jian Yang,Sailaja Vedantam,Tune H. Pers,Stefan Gustafsson,Audrey Y. Chu,K. Estrada,Jian'an Luan,Zoltán Kutalik,Najaf Amin,Martin L. Buchkovich,Damien C. Croteau-Chonka,Felix R. Day,Yanan Duan,Tove Fall,Rudolf S N Fehrmann,Teresa Ferreira,Anne U. Jackson,Juha Karjalainen,Ken Sin Lo,Adam E. Locke,Reedik Mägi,Evelin Mihailov,Eleonora Porcu,Joshua C. Randall,André Scherag,Anna A. E. Vinkhuyzen,Harm-Jan Westra,Thomas W. Winkler,Tsegaselassie Workalemahu,Jing Hua Zhao,Devin Absher,Eva Albrecht,Denise Anderson,Jeffrey Baron,Marian Beekman,Ayse Demirkan,Georg Ehret,Bjarke Feenstra,Mary F. Feitosa,Krista Fischer,Ross M. Fraser,Anuj Goel,Jian Gong,Anne E. Justice,Stavroula Kanoni,Marcus E. Kleber,K. Kristiansson,Unhee Lim,Vaneet Lotay,Julian C. Lui,Massimo Mangino,Irene Mateo Leach,Carolina Medina-Gomez,Mike A. Nalls,Dale R. Nyholt,Cameron D. Palmer,Dorota Pasko,Sonali Pechlivanis,Inga Prokopenko,Janina S. Ried,Stephan Ripke,Dmitry Shungin,Alena Stančáková,Rona J. Strawbridge,Yun Ju Sung,Toshiko Tanaka,Alexander Teumer,Stella Trompet,Sander W. van der Laan,Jessica van Setten,Jana V. van Vliet-Ostaptchouk,Zhaoming Wang,Loic Yengo,Weihua Zhang,Uzma Afzal,Johan Ärnlöv,Gillian M. Arscott,Stefania Bandinelli,Amy Barrett,Claire Bellis,Amanda J. Bennett,Christian Berne,Matthias Blüher,Jennifer L. Bolton,Yvonne Böttcher,Heather A. Boyd,Marcel Bruinenberg,Brendan M. Buckley,Steven Buyske,Ida Henriette Caspersen,Peter S. Chines,Robert Clarke,Simone Claudi-Boehm,Mark E. Cooper,E. Warwick Daw,Pim A. de Jong,Joris Deelen,Graciela Delgado,Josh C. Denny,Rosalie A.M. Dhonukshe-Rutten,Maria Dimitriou,Alex S. F. Doney,Marcus Dörr,Niina Eklund,Elodie Eury,Lasse Folkersen,Melissa E. Garcia,Frank Geller,Vilmantas Giedraitis,Alan S. Go,Harald Grallert,Tanja B. Grammer,Jürgen Gräßler,Henrik Grönberg,Lisette C P G M de Groot,C J Groves,Jeffrey Haessler,Per Hall,T. Haller,Göran Hallmans,Anke Hannemann,Catharina A. Hartman,Maija Hassinen,Caroline Hayward,Nancy L. Heard-Costa,Quinta Helmer,Gibran Hemani,Anjali K. Henders,Hans L. Hillege,Mark A. Hlatky,Wolfgang Hoffmann,Per Hoffmann,Oddgeir L. Holmen,Jeanine J. Houwing-Duistermaat,Thomas Illig,Aaron Isaacs,Alan L. James,Janina M. Jeff,Berit Johansen,Åsa Johansson,Jennifer Jolley,Thorhildur Juliusdottir,Juhani Junttila,Abel N. Kho,Leena Kinnunen,Norman Klopp,Thomas Kocher,Wolfgang Kratzer,Peter Lichtner,Lars Lind,Jaana Lindström,Stéphane Lobbens,Mattias Lorentzon,Yingchang Lu,Valeriya Lyssenko,Patrik K. E. Magnusson,Anubha Mahajan,Marc R. Maillard,Wendy L. McArdle,Colin A. McKenzie,Stela McLachlan,Paul J. McLaren,Cristina Menni,Sigrun Merger,Lili Milani,Alireza Moayyeri,Keri L. Monda,M. A. Morken,Gabriele Müller,Martina Müller-Nurasyid,A.W. Musk,Narisu Narisu,Matthias Nauck,Ilja M. Nolte,Markus M. Nöthen,Laticia Oozageer,Stefan Pilz,Nigel W. Rayner,Frida Renström,Neil R. Robertson,Lynda M. Rose,Ronan Roussel,Serena Sanna,Hubert Scharnagl,Salome Scholtens,Fredrick R. Schumacher,Heribert Schunkert,Robert A. Scott,J Sehmi,Thomas Seufferlein,Jianxin Shi,Karri Silventoinen,Johannes H. Smit,Albert V. Smith,Joanna Smolonska,Alice V. Stanton,Kathleen Stirrups,David J. Stott,Heather M. Stringham,Johan Sundström,Morris A. Swertz,Ann-Christine Syvänen,Bamidele O. Tayo,Gudmar Thorleifsson,Jonathan P. Tyrer,Suzanne C. van Dijk,Natasja M. van Schoor,Nathalie van der Velde,Diana van Heemst,Floor V. A. van Oort,S. H. H. M. Vermeulen,Niek Verweij,Judith M. Vonk,Lindsay L. Waite,Melanie Waldenberger,Roman Wennauer,Lynne R. Wilkens,Christina Willenborg,Tom Wilsgaard,Mary K. Wojczynski,Andrew Wong,Alan F. Wright,Qunyuan Zhang,Dominique Arveiler,Stephan J. L. Bakker,John Beilby,Richard N. Bergman,Sven Bergmann,Reiner Biffar,John Blangero,Dorret I. Boomsma,Stefan R. Bornstein,Pascal Bovet,Paolo Brambilla,Morris J. Brown,Harry Campbell,Mark J. Caulfield,Aravinda Chakravarti,Rory Collins,Francis S. Collins,Dana C. Crawford,L. Adrienne Cupples,John Danesh,Ulf de Faire,Hester M. den Ruijter,Raimund Erbel,Jeanette Erdmann,Johan G. Eriksson,Martin Farrall,Ele Ferrannini,Jean Ferrières,Ian Ford,Nita G. Forouhi,Terrence Forrester,Ron T. Gansevoort,Pablo V. Gejman,Christian Gieger,Alain Golay,Omri Gottesman,Vilmundur Gudnason,Ulf Gyllensten,David W. Haas,Alistair S. Hall,Tamara B. Harris,Andrew T. Hattersley,Andrew C. Heath,Christian Hengstenberg,Andrew A. Hicks,Lucia A. Hindorff,Aroon D. Hingorani,Albert Hofman,G. Kees Hovingh,Steve E. Humphries,Steven C. Hunt,Elina Hyppönen,Kevin B. Jacobs,Marjo-Riitta Järvelin,Pekka Jousilahti,Antti Jula,Jaakko Kaprio,John J. P. Kastelein,Manfred Kayser,Frank Kee,Keinänen-Kiukaanniemi S,Lambertus A. Kiemeney,Jaspal S. Kooner,Charles Kooperberg,Seppo Koskinen,Peter Kovacs,Aldi T. Kraja,Meena Kumari,Johanna Kuusisto,Timo A. Lakka,Claudia Langenberg,Loic Le Marchand,Terho Lehtimäki,Sara Lupoli,Pamela A. F. Madden,Satu Männistö,Paolo Manunta,Andre Marette,Tara C. Matise,Barbara McKnight,Thomas Meitinger,Frans L. Moll,Grant W. Montgomery,Andrew D. Morris,Andrew P. Morris,Jeffrey C. Murray,Mari Nelis,Claes Ohlsson,Albertine J. Oldehinkel,Ken K. Ong,Willem H. Ouwehand,Gerard Pasterkamp,Annette Peters,Peter P. Pramstaller,Jackie F. Price,Lu Qi,Olli T. Raitakari,Tuomo Rankinen,Dabeeru C. Rao,Treva Rice,Marylyn D. Ritchie,Igor Rudan,Veikko Salomaa,Nilesh J. Samani,Jouko Saramies,Mark A. Sarzynski,Peter E. H. Schwarz,Sylvain Sebert,Peter S. Sever,Alan R. Shuldiner,Juha Sinisalo,Valgerdur Steinthorsdottir,Ronald P. Stolk,Jean-Claude Tardif,A Tönjes,Angelo Tremblay,Elena Tremoli,Jarmo Virtamo,Marie-Claude Vohl,Philippe Amouyel,Folkert W. Asselbergs,Themistocles L. Assimes,Murielle Bochud,Bernhard O. Boehm,Eric Boerwinkle,Erwin P. Bottinger,Claude Bouchard,Stéphane Cauchi,John C. Chambers,Stephen J. Chanock,Richard S. Cooper,Paul I.W. de Bakker,George Dedoussis,Luigi Ferrucci,Paul W. Franks,Philippe Froguel,Leif Groop,Christopher A. Haiman,Anders Hamsten,M. Geoffrey Hayes,Jennie Hui,David J. Hunter,Kristian Hveem,J. Wouter Jukema,Robert C. Kaplan,Mika Kivimäki,Diana Kuh,Markku Laakso,Yongmei Liu,Nicholas G. Martin,Winfried März,Mads Melbye,Susanne Moebus,Patricia B. Munroe,Inger Njølstad,Ben A. Oostra,Colin N. A. Palmer,Nancy L. Pedersen,Markus Perola,Louis Pérusse,Ulrike Peters,Joseph E. Powell,Chris Power,Thomas Quertermous,Rainer Rauramaa,Eva Reinmaa,Paul M. Ridker,Fernando Rivadeneira,Jerome I. Rotter,T. Saaristo,Danish Saleheen,David Schlessinger,P. Eline Slagboom,Harold Snieder,Tim D. Spector,Konstantin Strauch,Michael Stumvoll,Jaakko Tuomilehto,Matti Uusitupa,Pim van der Harst,Henry Völzke,Mark Walker,Nicholas J. Wareham,Hugh Watkins,H.-Erich Wichmann,James F. Wilson,Pieter Zanen,Panos Deloukas,Iris M. Heid,Cecilia M. Lindgren,Karen L. Mohlke,Elizabeth K. Speliotes,Unnur Thorsteinsdottir,Inês Barroso,Caroline S. Fox,Kari E. North,David P. Strachan,Jacques S. Beckmann,Sonja I. Berndt,Michael Boehnke,Ingrid B. Borecki,Mark I. McCarthy,Andres Metspalu,Kari Stefansson,André G. Uitterlinden,Cornelia M. van Duijn,Lude Franke,Cristen J. Willer,Alkes L. Price,Guillaume Lettre,Ruth J. F. Loos,Michael N. Weedon,Erik Ingelsson,Jeffrey R. O'Connell,Gonçalo R. Abecasis,Daniel I. Chasman,Michael E. Goddard,Peter M. Visscher,Joel N. Hirschhorn,Timothy M. Frayling +444 more
TL;DR: This article identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height, and all common variants together captured 60% of heritability.
Journal ArticleDOI
Genetic variants associated with subjective well-being, depressive symptoms, and neuroticism identified through genome-wide analyses
Aysu Okbay,Bart M. L. Baselmans,Jan-Emmanuel De Neve,Patrick Turley,Michel G. Nivard,Mark Alan Fontana,S. Fleur W. Meddens,S. Fleur W. Meddens,S. Fleur W. Meddens,Richard Karlsson Linnér,Richard Karlsson Linnér,Richard Karlsson Linnér,Cornelius A. Rietveld,Jaime Derringer,Jacob Gratten,James J. Lee,Jimmy Z. Liu,Ronald de Vlaming,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Jadwiga Buchwald,Alana Cavadino,Alexis C. Frazier-Wood,Nicholas A. Furlotte,Victoria Garfield,Marie Henrike Geisel,Juan R. González,Saskia Haitjema,Robert Karlsson,Sander W. van der Laan,Karl-Heinz Ladwig,Jari Lahti,Sven J. van der Lee,Penelope A. Lind,Tian Liu,Lindsay K. Matteson,Evelin Mihailov,Michael B. Miller,Camelia C. Minică,Ilja M. Nolte,Dennis O. Mook-Kanamori,Peter J. van der Most,Christopher Oldmeadow,Yong Qian,Olli T. Raitakari,Olli T. Raitakari,Rajesh Rawal,Anu Realo,Anu Realo,Rico Rueedi,Rico Rueedi,Börge Schmidt,Albert V. Smith,Evie Stergiakouli,Toshiko Tanaka,Kent D. Taylor,Gudmar Thorleifsson,Juho Wedenoja,Juergen Wellmann,Harm-Jan Westra,Sara M. Willems,Wei Zhao,Najaf Amin,Andrew Bakshi,Sven Bergmann,Sven Bergmann,Gyda Bjornsdottir,Patricia A. Boyle,Samantha Cherney,Simon R. Cox,Gail Davies,Oliver S. P. Davis,Jun Ding,Nese Direk,Peter Eibich,Peter Eibich,Rebecca T. Emeny,Ghazaleh Fatemifar,Jessica D. Faul,Luigi Ferrucci,Andreas J. Forstner,Christian Gieger,Richa Gupta,Tamara B. Harris,Juliette Harris,Elizabeth G. Holliday,Jouke-Jan Hottenga,Philip L. De Jager,Philip L. De Jager,Philip L. De Jager,Marika Kaakinen,Marika Kaakinen,Eero Kajantie,Eero Kajantie,Ville Karhunen,Ivana Kolcic,Meena Kumari,Lenore J. Launer,Lude Franke,Ruifang Li-Gao,David C. Liewald,Marisa Koini,Anu Loukola,Pedro Marques-Vidal,Grant W. Montgomery,Miriam A. Mosing,Lavinia Paternoster,Alison Pattie,K. Petrovic,Laura Pulkki-Råback,Lydia Quaye,Katri Räikkönen,Igor Rudan,Rodney J. Scott,Jennifer A. Smith,Angelina R. Sutin,Angelina R. Sutin,Maciej Trzaskowski,Maciej Trzaskowski,Anna A. E. Vinkhuyzen,Lei Yu,Delilah Zabaneh,John Attia,David A. Bennett,Klaus Berger,Lars Bertram,Lars Bertram,Dorret I. Boomsma,Harold Snieder,Shun-Chiao Chang,Francesco Cucca,Ian J. Deary,Cornelia M. van Duijn,Johan G. Eriksson,Johan G. Eriksson,Ute Bültmann,Eco J. C. de Geus,Patrick J. F. Groenen,Vilmundur Gudnason,Torben Hansen,C.A. Hartman,Claire M. A. Haworth,Caroline Hayward,Andrew C. Heath,David A. Hinds,Elina Hyppönen,Elina Hyppönen,William G. Iacono,Marjo-Riitta Järvelin,Karl-Heinz Jöckel,Jaakko Kaprio,Jaakko Kaprio,Sharon L.R. Kardia,Liisa Keltikangas-Järvinen,Peter Kraft,Laura D. Kubzansky,Terho Lehtimäki,Patrik K. E. Magnusson,Nicholas G. Martin,Matt McGue,Andres Metspalu,Melinda Mills,Renée de Mutsert,Albertine J. Oldehinkel,Gerard Pasterkamp,Nancy L. Pedersen,Robert Plomin,Ozren Polasek,Christine Power,Stephen S. Rich,Frits R. Rosendaal,Hester M. den Ruijter,David Schlessinger,Helena Schmidt,Rauli Svento,Reinhold Schmidt,Behrooz Z. Alizadeh,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Tim D. Spector,John M. Starr,Kari Stefansson,Kari Stefansson,Andrew Steptoe,Antonio Terracciano,Antonio Terracciano,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Roy Thurik,Nicholas J. Timpson,Henning Tiemeier,André G. Uitterlinden,Peter Vollenweider,Gert G. Wagner,Gert G. Wagner,Gert G. Wagner,David R. Weir,Jian Yang,Dalton Conley,George Davey Smith,Albert Hofman,Albert Hofman,Magnus Johannesson,David Laibson,Sarah E. Medland,Michelle N. Meyer,Michelle N. Meyer,Joseph K. Pickrell,Tõnu Esko,Robert F. Krueger,Jonathan P. Beauchamp,Philipp Koellinger,Philipp Koellinger,Philipp Koellinger,Daniel J. Benjamin,Meike Bartels,David Cesarini +216 more
TL;DR: In this paper, the authors conducted genome-wide association studies of three phenotypes: subjective well-being (n = 298,420), depressive symptoms (n= 161,460), and neuroticism(n = 170,911).
Journal ArticleDOI
Common Carotid Intima-Media Thickness Measurements in Cardiovascular Risk Prediction A Meta-analysis
Hester M. den Ruijter,Sanne A.E. Peters,Todd J. Anderson,Annie Britton,Jacqueline M. Dekker,Marinus J.C. Eijkemans,Gunnar Engström,Gregory W. Evans,Jacqueline de Graaf,Diederick E. Grobbee,Diederick E. Grobbee,Bo Hedblad,Albert Hofman,Suzanne Holewijn,Ai Ikeda,Maryam Kavousi,Kazuo Kitagawa,Akihiko Kitamura,Hendrik Koffijberg,Eva Lonn,Matthias W. Lorenz,Ellisiv B. Mathiesen,Giel Nijpels,Shuhei Okazaki,Daniel H. O'Leary,Joseph F. Polak,Jackie F. Price,Christine Robertson,Christopher M. Rembold,Maria Rosvall,Tatjana Rundek,Jukka T. Salonen,Matthias Sitzer,Coen D.A. Stehouwer,Jacqueline C.M. Witteman,Karel G.M. Moons,Michiel L. Bots +36 more
TL;DR: The addition of common CIMT measurements to the Framingham Risk Score was associated with small improvement in 10-year risk prediction of first-time myocardial infarction or stroke, but this improvement is unlikely to be of clinical importance.
Journal ArticleDOI
The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study
Thomas W. Winkler,Anne E. Justice,Mariaelisa Graff,Llilda Barata,Mary F. Feitosa,Su H. Chu,Jacek Czajkowski,Tõnu Esko,Tove Fall,Tuomas O. Kilpeläinen,Yingchang Lu,Reedik Mägi,Evelin Mihailov,Tune H. Pers,Sina Rüeger,Alexander Teumer,Georg Ehret,Teresa Ferreira,Nancy L. Heard-Costa,Juha Karjalainen,Vasiliki Lagou,Anubha Mahajan,Michael D. Neinast,Inga Prokopenko,Jeannette Simino,Tanya M. Teslovich,Rick Jansen,Harm-Jan Westra,Charles C. White,Devin Absher,Tarunveer S. Ahluwalia,Shafqat Ahmad,Eva Albrecht,Alexessander Couto Alves,Jennifer L. Bragg-Gresham,Anton J. M. de Craen,Joshua C. Bis,Amélie Bonnefond,Gabrielle Boucher,Gemma Cadby,Yu-Ching Cheng,Charleston W. K. Chiang,Graciela Delgado,Ayse Demirkan,Nicole Dueker,Niina Eklund,Gudny Eiriksdottir,Joel Eriksson,Bjarke Feenstra,Krista Fischer,Francesca Frau,Tessel E. Galesloot,Frank Geller,Anuj Goel,Mathias Gorski,Tanja B. Grammer,Stefan Gustafsson,Saskia Haitjema,Jouke-Jan Hottenga,Jennifer E. Huffman,Anne U. Jackson,Kevin B. Jacobs,Åsa Johansson,Marika Kaakinen,Marcus E. Kleber,Jari Lahti,Irene Mateo Leach,Benjamin Lehne,Youfang Liu,Ken Sin Lo,Mattias Lorentzon,Jian'an Luan,Pamela A. F. Madden,Massimo Mangino,Barbara McKnight,Carolina Medina-Gomez,Keri L. Monda,May E. Montasser,Gabriele Müller,Martina Müller-Nurasyid,Ilja M. Nolte,Kalliope Panoutsopoulou,Laura Pascoe,Lavinia Paternoster,Nigel W. Rayner,Frida Renström,Federica Rizzi,Lynda M. Rose,Kathy Ryan,Perttu Salo,Serena Sanna,Hubert Scharnagl,Jianxin Shi,Albert V. Smith,Lorraine Southam,Alena Stančáková,Valgerdur Steinthorsdottir,Rona J. Strawbridge,Yun Ju Sung,Ioanna Tachmazidou,Toshiko Tanaka,Gudmar Thorleifsson,Stella Trompet,Natalia Pervjakova,Jonathan Tyrer,Liesbeth Vandenput,Sander W. van der Laan,Nathalie van der Velde,Jessica van Setten,Jana V. van Vliet-Ostaptchouk,Niek Verweij,Efthymia Vlachopoulou,Lindsay L. Waite,Sophie R. Wang,Zhaoming Wang,Sarah H. Wild,Christina Willenborg,James F. Wilson,Andrew Wong,Jian Yang,Loic Yengo,Laura M. Yerges-Armstrong,Lei Yu,Weihua Zhang,Jing Hua Zhao,Ehm A. Andersson,Stephan J. L. Bakker,Damiano Baldassarre,Karina Banasik,Matteo Barcella,Cristina Barlassina,Claire Bellis,Paola Benaglio,John Blangero,Matthias Blüher,Fabrice Bonnet,Lori L. Bonnycastle,Heather A. Boyd,Marcel Bruinenberg,Aron S. Buchman,Harry Campbell,Yii-Der Ida Chen,Peter S. Chines,Simone Claudi-Boehm,John B. Cole,Francis S. Collins,Eco J. C. de Geus,Lisette C. P. G. M. de Groot,Maria Dimitriou,Jubao Duan,Stefan Enroth,Elodie Eury,Aliki-Eleni Farmaki,Nita G. Forouhi,Nele Friedrich,Pablo V. Gejman,Bruna Gigante,Nicola Glorioso,Alan S. Go,Omri Gottesman,Jürgen Gräßler,Harald Grallert,Niels Grarup,Yu Mei Gu,Linda Broer,Annelies C. Ham,Torben Hansen,Tamara B. Harris,Catharina A. Hartman,Maija Hassinen,Nicholas D. Hastie,Andrew T. Hattersley,Andrew C. Heath,Anjali K. Henders,Dena G. Hernandez,Hans L. Hillege,Oddgeir L. Holmen,Kees Hovingh,Jennie Hui,Lise Lotte N. Husemoen,Nina Hutri-Kähönen,Pirro G. Hysi,Thomas Illig,Philip L. De Jager,Shapour Jalilzadeh,Torben Jørgensen,J. Wouter Jukema,Markus Juonala,Stavroula Kanoni,Maria Karaleftheri,Kay-Tee Khaw,Leena Kinnunen,Steven J. Kittner,Wolfgang Koenig,Ivana Kolcic,Peter Kovacs,Nikolaj T. Krarup,Wolfgang Kratzer,Janine Krüger,Diana Kuh,Meena Kumari,Theodosios Kyriakou,Claudia Langenberg,Lars Lannfelt,Chiara Lanzani,Vaneet Lotay,Lenore J. Launer,Karin Leander,Jaana Lindström,Allan Linneberg,Yan Ping Liu,Stéphane Lobbens,Robert Luben,Valeriya Lyssenko,Satu Männistö,Patrik K. E. Magnusson,Wendy L. McArdle,Cristina Menni,Sigrun Merger,Lili Milani,Grant W. Montgomery,Andrew P. Morris,Narisu Narisu,Mari Nelis,Ken K. Ong,Aarno Palotie,Louis Pérusse,Irene Pichler,Maria Grazia Pilia,Anneli Pouta,Myriam Rheinberger,Rasmus Ribel-Madsen,Marcus Richards,Kenneth Rice,Treva Rice,Carlo Rivolta,Veikko Salomaa,Alan R. Sanders,Mark A. Sarzynski,Salome Scholtens,Robert A. Scott,William R. Scott,Sylvain Sebert,Sebanti Sengupta,Bengt Sennblad,Thomas Seufferlein,Angela Silveira,P. Eline Slagboom,Jan Smit,Thomas Sparsø,Kathleen Stirrups,Ronald P. Stolk,Heather M. Stringham,Morris A. Swertz,Amy J. Swift,Ann-Christine Syvänen,Sian Tsung Tan,Barbara Thorand,Anke Tönjes,Angelo Tremblay,Emmanouil Tsafantakis,Peter J. van der Most,Uwe Völker,Marie-Claude Vohl,Judith M. Vonk,Melanie Waldenberger,Ryan W. Walker,Roman Wennauer,Elisabeth Widen,Gonneke Willemsen,Tom Wilsgaard,Alan F. Wright,M. Carola Zillikens,Suzanne C. van Dijk,Natasja M. van Schoor,Folkert W. Asselbergs,Paul I.W. de Bakker,Jacques S. Beckmann,John Beilby,David A. Bennett,Richard N. Bergman,Sven Bergmann,Carsten A. Böger,Bernhard O. Boehm,Eric Boerwinkle,Dorret I. Boomsma,Stefan R. Bornstein,Erwin P. Bottinger,Claude Bouchard,John C. Chambers,Stephen J. Chanock,Daniel I. Chasman,Francesco Cucca,Daniele Cusi,George Dedoussis,Jeanette Erdmann,Johan G. Eriksson,Denis A. Evans,Ulf de Faire,Martin Farrall,Luigi Ferrucci,Ian Ford,Lude Franke,Paul W. Franks,Philippe Froguel,Ron T. Gansevoort,Christian Gieger,Henrik Grönberg,Vilmundur Gudnason,Ulf Gyllensten,Per Hall,Anders Hamsten,Pim van der Harst,Caroline Hayward,Markku Heliövaara,Christian Hengstenberg,Andrew A. Hicks,Aroon D. Hingorani,Albert Hofman,Frank B. Hu,Heikki V. Huikuri,Kristian Hveem,Alan L. James,Joanne M. Jordan,Antti Jula,Mika Kähönen,Eero Kajantie,Sekar Kathiresan,Lambertus A. Kiemeney,Mika Kivimäki,Paul Knekt,Heikki A. Koistinen,Jaspal S. Kooner,Seppo Koskinen,Johanna Kuusisto,Winfried Maerz,Nicholas G. Martin,Markku Laakso,Timo A. Lakka,Terho Lehtimäki,Guillaume Lettre,Douglas F. Levinson,Lars Lind,Marja-Liisa Lokki,Pekka Mäntyselkä,Mads Melbye,Andres Metspalu,Braxton D. Mitchell,Frans L. Moll,Jeffrey C. Murray,Arthur W. Musk,Markku S. Nieminen,Inger Njølstad,Claes Ohlsson,Albertine J. Oldehinkel,Ben A. Oostra,Lyle J. Palmer,James S. Pankow,Gerard Pasterkamp,Nancy L. Pedersen,Oluf Pedersen,Brenda W.J.H. Penninx,Markus Perola,Annette Peters,Ozren Polasek,Peter P. Pramstaller,Bruce M. Psaty,Lu Qi,Thomas Quertermous,Olli T. Raitakari,Tuomo Rankinen,Rainer Rauramaa,Paul M. Ridker,John D. Rioux,Fernando Rivadeneira,Jerome I. Rotter,Igor Rudan,Hester M. den Ruijter,Juha Saltevo,Naveed Sattar,Heribert Schunkert,Peter Schwarz,Alan R. Shuldiner,Juha Sinisalo,Harold Snieder,Thorkild I. A. Sørensen,Tim D. Spector,Jan A. Staessen,Bandinelli Stefania,Unnur Thorsteinsdottir,Michael Stumvoll,Jean-Claude Tardif,Elena Tremoli,Jaakko Tuomilehto,André G. Uitterlinden,Matti Uusitupa,André L. M. Verbeek,Sita H. Vermeulen,Jorma Viikari,Veronique Vitart,Henry Völzke,Peter Vollenweider,Gérard Waeber,Mark Walker,Henri Wallaschofski,Nicholas J. Wareham,Hugh Watkins,Eleftheria Zeggini,Aravinda Chakravarti,Deborah J. Clegg,L. Adrienne Cupples,Penny Gordon-Larsen,Cashell E. Jaquish,Dabeeru C. Rao,Gonçalo R. Abecasis,Themistocles L. Assimes,Inês Barroso,Sonja I. Berndt,Michael Boehnke,Panos Deloukas,Caroline S. Fox,Leif Groop,David J. Hunter,Erik Ingelsson,Robert C. Kaplan,Mark I. McCarthy,Karen L. Mohlke,Jeffrey R. O'Connell,David Schlessinger,David P. Strachan,Kari Stefansson,Cornelia M. van Duijn,Joel N. Hirschhorn,Cecilia M. Lindgren,Iris M. Heid,Kari E. North,Ingrid B. Borecki,Zoltán Kutalik,Ruth J. F. Loos +438 more
TL;DR: In this paper, the authors performed meta-analyses of 114 studies with genome-wide chip and/or Metabochip data by the Genetic Investigation of Anthropometric Traits (GIANT) Consortium.