Christopher P Cheyne

TL;DR: An accumulation of evidence demonstrates that the risks associated with prenatal sodium VPA exposure include an increased prevalence of neurodevelopmental disorders, whether such disorders are discrete or represent the severe end of a continuum of altered neuro developmental functioning requires further investigation.

TL;DR: For example, this article found that children exposed to high-dose valproate had an 8-fold increased need for educational intervention relative to control children (adjusted relative risk, 95% CI 8.0, 2.5-19.7; p p p = 0.04) and a 6-fold increase in educational intervention (95% CI 1.4-18.0; p =0.01).

TL;DR: Preconception counseling should include discussion of neurodevelopmental outcomes for specific treatments and their doses and women should be made aware of the limited nature of the evidence base for newer antiepileptic drugs.

TL;DR: Incidence and point prevalence of visual problems in acute stroke is alarmingly high, affecting over half the survivors, and crucial information can be provided on visual status and its functional significance to the stroke team, patients and carers, enabling early intervention.

TL;DR: Children exposed to LEV in utero were superior in their language and motor development in comparison to children exposed to VPA, and this information should be used collaboratively between health care professionals and WWE when deciding on women's preferred choice of antiepileptic drug.