Christopher R. Kauffman

TL;DR: Objective OCT criteria are highly sensitive and specific for characterizing different types of atherosclerotic plaques in vitro and will provide a basis for the interpretation of intracoronary OCT images obtained from patients.

TL;DR: The high contrast and resolution of OCT enables the quantification of macrophages within fibrous caps and suggests that this technology may be well suited for identifying vulnerable plaques in patients.

TL;DR: Intracoronary OCT for monitoring stent deployment is feasible and provides superior contrast and resolution of arterial pathology than IVUS.

TL;DR: By providing a means of detecting increases in plaque macrophage content before an acute event, this technique may aid in determining prognosis and guiding preventive therapy and demonstrate that increases in both multi-focal and focal macrophages densities are highly correlated with symptom severity.

TL;DR: By providing a means of detecting increases in plaque macrophage content before an acute event, this technique may aid in determining prognosis and guiding preventive therapy and demonstrate that increases in both multi-focal and focal macrophages densities are highly correlated with symptom severity.