M
Milen Shishkov
Researcher at Harvard University
Publications - 90
Citations - 9660
Milen Shishkov is an academic researcher from Harvard University. The author has contributed to research in topics: Optical coherence tomography & Optical fiber. The author has an hindex of 36, co-authored 90 publications receiving 9294 citations.
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Journal ArticleDOI
Characterization of Human Atherosclerosis by Optical Coherence Tomography
Hiroshi Yabushita,Brett E. Bouma,Stuart L. Houser,H. Thomas Aretz,Ik-Kyung Jang,Kelly Schlendorf,Christopher R. Kauffman,Milen Shishkov,Dong-Heon Kang,Elkan F. Halpern,Guillermo J. Tearney +10 more
TL;DR: Objective OCT criteria are highly sensitive and specific for characterizing different types of atherosclerotic plaques in vitro and will provide a basis for the interpretation of intracoronary OCT images obtained from patients.
Journal ArticleDOI
Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography: comparison with intravascular ultrasound.
Ik-Kyung Jang,Brett E. Bouma,Dong-Heon Kang,Dong-Heon Kang,Seung-Jung Park,Seong-Wook Park,Ki-Bae Seung,Kyu-Bo Choi,Milen Shishkov,Kelly Schlendorf,Eugene Pomerantsev,Stuart L. Houser,H. Thomas Aretz,Guillermo J. Tearney +13 more
TL;DR: Comparison between OCT and histology demonstrated that lipid-rich plaques and fibrous plaques have distinct OCT characteristics, and intracoronary OCT appears to be feasible and safe.
Journal ArticleDOI
In Vivo Characterization of Coronary Atherosclerotic Plaque by Use of Optical Coherence Tomography
Ik-Kyung Jang,Guillermo J. Tearney,Briain D. MacNeill,Masamichi Takano,Fabian Moselewski,Nicusor Iftima,Milen Shishkov,Stuart L. Houser,H. Thomas Aretz,Elkan F. Halpern,Brett E. Bouma +10 more
TL;DR: OCT is a safe and effective modality for characterizing coronary atherosclerotic plaques in vivo and thin-cap fibroatheroma was more frequently observed in patients with AMI or ACS than SAP.
Journal ArticleDOI
Quantification of Macrophage Content in Atherosclerotic Plaques by Optical Coherence Tomography
Guillermo J. Tearney,Hiroshi Yabushita,Stuart L. Houser,H. Thomas Aretz,Ik-Kyung Jang,Kelly Schlendorf,Christopher R. Kauffman,Milen Shishkov,Elkan F. Halpern,Brett E. Bouma +9 more
TL;DR: The high contrast and resolution of OCT enables the quantification of macrophages within fibrous caps and suggests that this technology may be well suited for identifying vulnerable plaques in patients.
Journal ArticleDOI
Comprehensive volumetric optical microscopy in vivo.
Seok Hyun Yun,Guillermo J. Tearney,Guillermo J. Tearney,Benjamin J. Vakoc,Milen Shishkov,Wang-Yuhl Oh,Adrien E. Desjardins,Adrien E. Desjardins,Melissa J. Suter,Raymond Chan,John A. Evans,Ik-Kyung Jang,Norman S. Nishioka,Norman S. Nishioka,Johannes F. de Boer,Johannes F. de Boer,Brett E. Bouma,Brett E. Bouma +17 more
TL;DR: The pilot study results suggest that this fiber-optic imaging technique termed optical frequency-domain imaging (OFDI) may be a useful clinical tool for comprehensive diagnostic imaging for epithelial disease and for evaluating coronary pathology and iatrogenic effects.