C
Christopher S. Regens
Researcher at University of Illinois at Urbana–Champaign
Publications - 20
Citations - 978
Christopher S. Regens is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Catalysis & Palladium. The author has an hindex of 9, co-authored 19 publications receiving 866 citations. Previous affiliations of Christopher S. Regens include Urbana University & Bristol-Myers Squibb.
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Journal ArticleDOI
Palladium-catalyzed cross-coupling reactions of organosilanols and their salts: practical alternatives to boron- and tin-based methods.
TL;DR: A new paradigm for palladium-catalyzed, silicon-based cross-coupling reactions that employs organosilanols, a previously underutilized class of silicon reagents is introduced to address the "fluoride problem".
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Total synthesis of papulacandin D.
Journal ArticleDOI
Mono-Oxidation of Bidentate Bis-phosphines in Catalyst Activation: Kinetic and Mechanistic Studies of a Pd/Xantphos-Catalyzed C-H Functionalization.
Yining Ji,R. Erik Plata,Christopher S. Regens,Michael B. Hay,Michael A. Schmidt,Thomas M. Razler,Yuping Qiu,Geng Peng,Yi Hsiao,Thorsten Rosner,Martin D. Eastgate,Donna G. Blackmond +11 more
TL;DR: Kinetic, spectroscopic, crystallographic, and computational studies probing a Pd-catalyzed C-H arylation reaction reveal that mono-oxidation of the bis-phosphine ligand is critical for the formation of the active catalyst.
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Total Synthesis of Papulacandin D
TL;DR: A total synthesis of (+)-papulacandin D which shows an antifungal activity is reported, and was accomplished in 31 steps overall from commercial starting materials.
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Total Synthesis of (+)-Papulacandin D
TL;DR: A critical element in the successful execution of the synthesis of (+)-papulacandin D was the development of a suitable protecting group strategy that satisfied a number of stringent criteria.