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Chul Woo Kim

Researcher at New Generation University College

Publications -  201
Citations -  7105

Chul Woo Kim is an academic researcher from New Generation University College. The author has contributed to research in topics: Cancer & Apoptosis. The author has an hindex of 43, co-authored 186 publications receiving 6335 citations. Previous affiliations of Chul Woo Kim include Seoul National University Hospital.

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Elevated Levels of Cholesterol-Rich Lipid Rafts in Cancer Cells Are Correlated with Apoptosis Sensitivity Induced by Cholesterol-Depleting Agents

TL;DR: It is reported that cholesterol depletion using methyl-beta cyclodextrin caused anoikis-like apoptosis, which in A431 cells involved decreased raft levels, Bcl-xL down-regulation, caspase-3 activation, and Akt inactivation regardless of epidermal growth factor receptor activation.
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Exosomes derived from mesenchymal stem cells suppress angiogenesis by down-regulating VEGF expression in breast cancer cells.

TL;DR: The collective results suggest that MSC-derived exosomes may serve as a significant mediator of cell-to-cell communication within the tumor microenvironment and suppress angiogenesis by transferring anti-angiogenic molecules.
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Exosome derived from epigallocatechin gallate treated breast cancer cells suppresses tumor growth by inhibiting tumor-associated macrophage infiltration and M2 polarization

TL;DR: It is demonstrated that EGCG up-regulates miR-16 in tumor cells, which can be transferred to TAM via exosomes and inhibits TAM infiltration and M2 polarization, and a novel mechanism by which E GCG exerts anti-tumor activity via regulation of TAM in tumor microenvironment is suggested.
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Hepatitis B virus X protein induces angiogenesis by stabilizing hypoxia-inducible factor-1α

TL;DR: The data suggest that HBx stabilizes HIF‐1α and leads to angiogenesis during hepatocarcinogenesis, and this work shows that microvessels are more abundant in the dysplastic lesion than in the non‐neoplastic region.