C
Cilia Abad
Researcher at Charles University in Prague
Publications - 33
Citations - 528
Cilia Abad is an academic researcher from Charles University in Prague. The author has contributed to research in topics: Lipid peroxidation & Red blood cell. The author has an hindex of 11, co-authored 25 publications receiving 287 citations. Previous affiliations of Cilia Abad include Venezuelan Institute for Scientific Research.
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Journal ArticleDOI
Oxidative stress: Normal pregnancy versus preeclampsia
Delia I. Chiarello,Cilia Abad,Deliana Rojas,Fernando Toledo,Carmen Vázquez,Alfonso Mate,Luis Sobrevia,Luis Sobrevia,Luis Sobrevia,Reinaldo Marín +9 more
TL;DR: This review focuses on the mechanism of oxidative stress in pregnancy as well as its involvement and consequences on the human pregnancy-specific clinical syndrome preeclampsia.
Journal ArticleDOI
Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia.
Reinaldo Marín,Delia I. Chiarello,Cilia Abad,Deliana Rojas,Fernando Toledo,Luis Sobrevia,Luis Sobrevia,Luis Sobrevia +7 more
TL;DR: The mitochondrial dysfunction in both eoPE and loPE is summarized and interventional studies in patients with preeclampsia using the coenzyme Q10, a key molecule in the electron transport chain, suggest that agents increasing the antioxidant capacity of the placenta may be protective of developing preeClampsia.
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Effect of magnesium sulfate on the calcium-stimulated adenosine triphosphatase activity and lipid peroxidation of red blood cell membranes from preeclamptic women.
Cilia Abad,Alejandro Teppa-Garrán,Teresa Proverbio,Sandy Piñero,Fulgencio Proverbio,Reinaldo Marín +5 more
TL;DR: Data indicate that MgSO(4) treatment of preeclamptic pregnant women modifies both the Ca-ATPase activity and the level of lipid peroxidation of their red blood cell membranes, reaching values similar to those of normotensive pregnant women.
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Serotonin homeostasis in the materno-foetal interface at term: Role of transporters (SERT/SLC6A4 and OCT3/SLC22A3) and monoamine oxidase A (MAO-A) in uptake and degradation of serotonin by human and rat term placenta.
Rona Karahoda,Hana Horackova,Petr Kastner,Andreas Matthios,Lukas Cerveny,Radim Kučera,Marian Kacerovsky,Jurjen Duintjer Tebbens,Alexandre Bonnin,Cilia Abad,Frantisek Staud +10 more
TL;DR: A novel model of serotonin homeostasis in the term placenta is proposed with special focus on the protective role of organic cation transporter 3 (OCT3/SLC22A3).
Journal ArticleDOI
Dynamics of Tryptophan Metabolic Pathways in Human Placenta and Placental-Derived Cells: Effect of Gestation Age and Trophoblast Differentiation.
Rona Karahoda,Cilia Abad,Hana Horackova,Petr Kastner,Jonas Zaugg,Lukas Cerveny,Radim Kučera,Christiane Albrecht,Frantisek Staud +8 more
TL;DR: The data provide the first comprehensive evidence of changes in placental homeostasis of tryptophan and its metabolites as a function of gestational age, which is critical for proper placental function and fetal development.