C
Claudia Bouvier
Researcher at Vollum Institute
Publications - 2
Citations - 683
Claudia Bouvier is an academic researcher from Vollum Institute. The author has contributed to research in topics: Nociceptin receptor & OGFr. The author has an hindex of 2, co-authored 2 publications receiving 671 citations.
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Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type
James R. Bunzow,Carmen Sáez,Marty Mortrud,Claudia Bouvier,John T. Williams,Malcolm J. Low,David K. Grandy,David K. Grandy +7 more
TL;DR: In situ hybridization analysis revealed that LC132 mRNA is highly expressed in several rat brain areas, including the cerebral cortex, thalamus, subfornical organ, habenula, hypothalamus, central gray, dorsal raphe, locus coeruleus and the dorsal horn of the spinal cord.
Journal ArticleDOI
Characterization and distribution of a cloned rat μ-opioid receptor
James R. Bunzow,Ge Zhang,Claudia Bouvier,Carmen Sáez,Oline K. Rønnekleiv,Martin J. Kelly,David K. Grandy,David K. Grandy +7 more
TL;DR: The rank order potencies of these ligands, the stereospecificity of levorphanol, and morphine's subnanomolar Ki are consistent with a μ‐opioid binding site, and this opioid‐binding site is functionally coupled to G proteins.