C
Conelius Ngwa
Researcher at University of Texas Health Science Center at Houston
Publications - 12
Citations - 153
Conelius Ngwa is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Medicine & Microglia. The author has an hindex of 3, co-authored 7 publications receiving 49 citations. Previous affiliations of Conelius Ngwa include Baylor College of Medicine.
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Journal ArticleDOI
Microglial IRF5-IRF4 regulatory axis regulates neuroinflammation after cerebral ischemia and impacts stroke outcomes
Abdullah Al Mamun,Anjali Chauhan,Shaohua Qi,Conelius Ngwa,Yan Xu,Romana Sharmeen,Amy L. Hazen,Jun Li,Jaroslaw Aronowski,Louise D. McCullough,Fudong Liu +10 more
TL;DR: It is demonstrated that the manipulation of the axis alters stroke outcomes, an important finding, as the IRF5-IRF4 regulatory axis potentially provides stroke scientists with a therapeutic target for the treatment of stroke.
Journal ArticleDOI
X chromosome escapee genes are involved in ischemic sexual dimorphism through epigenetic modification of inflammatory signals.
Shaohua Qi,Abdullah Al Mamun,Conelius Ngwa,Sharmeen Romana,Rodney M. Ritzel,Arthur P. Arnold,Louise D. McCullough,Fudong Liu +7 more
TL;DR: In this paper, RNA-seq was used to identify the X escapee genes involved in stroke, and the expression of these genes (kdm5c/kdm6a) were confirmed in four core genotypes (FCG) mice and in post-mortem human stroke brains by immunohistochemistry (IHC), Western blot, and RT-PCR.
Journal Article
CD200-CD200R signaling and diseases: a potential therapeutic target?
Conelius Ngwa,Fudong Liu +1 more
TL;DR: This review focused on cellular expression of the signaling, the effects on immune cell activation, and the function in pathological procedures of neurodegenerative diseases, in both clinical and experimental disease models.
Journal ArticleDOI
A Hyperfluorinated Hydrophilic Molecule for Aqueous 19F MRI Contrast Media.
Eric A. Tanifum,Eric A. Tanifum,Laxman Devkota,Conelius Ngwa,Andrew Badachhape,Ketan B. Ghaghada,Ketan B. Ghaghada,Jonathan Romero,Robia G. Pautler,Ananth Annapragada,Ananth Annapragada +10 more
TL;DR: A hyperfluorinated hydrophilic organoflourine molecule, ET1084, with ∼24 wt.
Journal ArticleDOI
Age and sex differences in primary microglia culture: A comparative study
TL;DR: In this paper, the authors showed that the aged microglia had larger cell bodies, more cytoplasmic inclusions, and enhanced phagocytosis than the neonatal cells.