C
Conor L. Evans
Researcher at Harvard University
Publications - 165
Citations - 8097
Conor L. Evans is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 28, co-authored 140 publications receiving 7106 citations. Previous affiliations of Conor L. Evans include Dartmouth College.
Papers
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Journal ArticleDOI
PLGA nanoparticle encapsulation reduces toxicity while retaining the therapeutic efficacy of EtNBS-PDT in vitro
Hsin-I Hung,Oliver Klein,Sam W. Peterson,Sarah R. Rokosh,Sam Osseiran,Sam Osseiran,Nicholas H. Nowell,Conor L. Evans +7 more
TL;DR: Interestingly, encapsulation of the compound within poly(lactic-co-glycolic acid) ( PLGA) nanoparticles (PLGA-EtNBS) was found to significantly reduce EtNBS dark toxicity while completely retaining the molecule’s cytotoxicity in both normoxic and hypoxic conditions.
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In vivo coherent Raman imaging of the melanomagenesis-associated pigment pheomelanin
Hequn Wang,Sam Osseiran,Sam Osseiran,Vivien Igras,Alexander J. Nichols,Alexander J. Nichols,Elisabeth Roider,Joachim Pruessner,Hensin Tsao,David E. Fisher,Conor L. Evans +10 more
TL;DR: In this article, the distribution of pheomelanin in cells and tissues can be visually characterized non-destructively and noninvasively in vivo with coherent anti-Stokes Raman scattering (CARS) microscopy, a label free vibrational imaging technique.
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Characterizing stratum corneum structure, barrier function, and chemical content of human skin with coherent Raman scattering imaging.
Sam Osseiran,Jomer Dela Cruz,Sinyoung Jeong,Hequn Wang,Christina G. Fthenakis,Conor L. Evans +5 more
TL;DR: Results suggest that hydration restored by the humectant agents may not be retained by the corneocytes in the ex vivo model system, and these techniques can be used to measure uptake and efficacy of topical compounds in order to better understand their mode of action and improve therapeutic applications.
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Bright, “Clickable” Porphyrins for the Visualization of Oxygenation under Ambient Light
TL;DR: A paint-on liquid bandage containing a new, click-synthesized porphyrin dendrimer has been used to map oxygenation across an ex vivo porcine skin burn model.
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Multiphoton excited hemoglobin fluorescence and third harmonic generation for non-invasive microscopy of stored blood.
Ilyas Saytashev,Rachel Glenn,Gabrielle A. Murashova,Sam Osseiran,Dana M. Spence,Conor L. Evans,Marcos Dantus +6 more
TL;DR: It is found that both TPEF and THG microscopy can be used to examine erythrocyte morphology non-invasively without breaching a blood storage bag.