C
Conor L. Evans
Researcher at Harvard University
Publications - 165
Citations - 8097
Conor L. Evans is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 28, co-authored 140 publications receiving 7106 citations. Previous affiliations of Conor L. Evans include Dartmouth College.
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Journal ArticleDOI
PuraMatrix encapsulation of cancer cells.
TL;DR: When encapsulated in PuraMatrix, OVCAR-5 cells assemble into three dimensional acinar structures that more closely resemble the morphology of micrometastatic nodules observed in the clinic than monolayer in vitro models.
Journal Article
PLGA nanoparticle encapsulation reduces toxicity while retaining the therapeutic efficacy of EtNBS-PDT in vitro
Hsin-I Hung,Oliver Klein,Sam W. Peterson,Sarah R. Rokosh,Nicholas H. Nowell,Conor L. Evans,Sam Osseiran +6 more
TL;DR: In this article, the authors evaluated the use of nanoparticle encapsulation to overcome the dark toxicity of photosensitizers such as the small cationic molecule EtNBS (5-ethylamino-9-diethyl-aminobenzo[a]phenothiazinium chloride).
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Structure-function relationships of Nile blue (EtNBS) derivatives as antimicrobial photosensitizers
Daniela Vecchio,Brijesh Bhayana,Liyi Huang,Elisa Carrasco,Elisa Carrasco,Elisa Carrasco,Conor L. Evans,Michael R. Hamblin,Michael R. Hamblin +8 more
TL;DR: Three separate pieces of structure-activity relationship data are provided for antimicrobial photosensitizers based on the EtNBS backbone, including the hypothesis that 1-substitution distorts the planar structure of the conjugated rings.
Journal ArticleDOI
Longitudinal, label-free, quantitative tracking of cell death and viability in a 3D tumor model with OCT
TL;DR: OCT was shown to be capable of evaluating 3D spheroid treatment response even when traditional viability assays failed, and synergy between PDT and the standard-of-care chemotherapeutic carboplatin that evolved over time was revealed.
Journal ArticleDOI
Transient Alterations of Cutaneous Sensory Nerve Function by Noninvasive Cryolipolysis
Lilit Garibyan,Laura Cornelissen,William H. Sipprell,Joachim Pruessner,Sarina B. Elmariah,Tuan Luo,Ethan A. Lerner,Yookyung Jung,Conor L. Evans,David Zurakowski,Charles B. Berde,R. Rox Anderson +11 more
TL;DR: The data suggest that controlled skin cooling to specifically target cutaneous nerve fibers has the potential to be useful for prolonged relief of cutaneous pain and might have a use as a research tool to isolate and study cutaneous itch-sensing nerves in human skin.