C
Constance Ducar
Researcher at Johns Hopkins University
Publications - 3
Citations - 2518
Constance Ducar is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Nevirapine & Population. The author has an hindex of 3, co-authored 3 publications receiving 2485 citations.
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Journal ArticleDOI
Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial
Laura Guay,Philippa Musoke,Thomas Fleming,Danstan Bagenda,Melissa Allen,Clemensia Nakabiito,Joseph Sherman,Paul M Bakaki,Constance Ducar,Martina Deseyve,Lynda Emel,Mark Mirochnick,Mary Glenn Fowler,Lynne M. Mofenson,Paolo G. Miotti,Kevin Dransfield,Dorothy Bray,Francis Mmiro,J. Brooks Jackson +18 more
TL;DR: Nevirapine lowered the risk of HIV-1 transmission during the first 14-16 weeks of life by nearly 50% in a breastfeeding population, suggesting this simple and inexpensive regimen could decrease mother-to-child HIV- 1 transmission in less-developed countries.
Journal ArticleDOI
Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial
J. Brooks Jackson,Philippa Musoke,Thomas Fleming,Thomas Fleming,Laura Guay,Danstan Bagenda,Melissa Allen,Clemensia Nakabiito,Joseph Sherman,Paul M Bakaki,Maxensia Owor,Constance Ducar,Martina Deseyve,Anthony Mwatha,Lynda Emel,Corey Duefield,Mark Mirochnick,Mary Glenn Fowler,Lynne M. Mofenson,Paolo G. Miotti,Maria Gigliotti,Dorothy Bray,Francis Mmiro +22 more
TL;DR: Intrapartum/ne ononatal nevirapine significantly lowered HIV-1 transmission risk in a breastfeeding population in Uganda compared with a short intrapartu/neonatal zidovudine regimen.
Journal ArticleDOI
A study of the safety immunology virology and microbiology of adjunctive etanercept in HIV-1-associated tuberculosis.
Robert S. Wallis,Peter Kyambadde,John L. Johnson,Libby Horter,Rodney Kittle,Monika Pohle,Constance Ducar,Monica Millard,Harriet Mayanja-Kizza,Christopher C. Whalen,Alphonse Okwera +10 more
TL;DR: Etanercept can be safely administered during the initial treatment of pulmonary tuberculosis, and trends towards superior responses to tuberculosis treatment were evident in etanercept-treated subjects in body mass, performance score, number of involved lung zones, cavitary closure, and time to sputum culture conversion.