D
Danstan Bagenda
Researcher at University of Nebraska Medical Center
Publications - 65
Citations - 4442
Danstan Bagenda is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Population & Nevirapine. The author has an hindex of 25, co-authored 61 publications receiving 4210 citations. Previous affiliations of Danstan Bagenda include College of Health Sciences, Bahrain & Johns Hopkins University.
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Journal ArticleDOI
Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: HIVNET 012 randomised trial
Laura Guay,Philippa Musoke,Thomas Fleming,Danstan Bagenda,Melissa Allen,Clemensia Nakabiito,Joseph Sherman,Paul M Bakaki,Constance Ducar,Martina Deseyve,Lynda Emel,Mark Mirochnick,Mary Glenn Fowler,Lynne M. Mofenson,Paolo G. Miotti,Kevin Dransfield,Dorothy Bray,Francis Mmiro,J. Brooks Jackson +18 more
TL;DR: Nevirapine lowered the risk of HIV-1 transmission during the first 14-16 weeks of life by nearly 50% in a breastfeeding population, suggesting this simple and inexpensive regimen could decrease mother-to-child HIV- 1 transmission in less-developed countries.
Journal ArticleDOI
Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial
J. Brooks Jackson,Philippa Musoke,Thomas Fleming,Thomas Fleming,Laura Guay,Danstan Bagenda,Melissa Allen,Clemensia Nakabiito,Joseph Sherman,Paul M Bakaki,Maxensia Owor,Constance Ducar,Martina Deseyve,Anthony Mwatha,Lynda Emel,Corey Duefield,Mark Mirochnick,Mary Glenn Fowler,Lynne M. Mofenson,Paolo G. Miotti,Maria Gigliotti,Dorothy Bray,Francis Mmiro +22 more
TL;DR: Intrapartum/ne ononatal nevirapine significantly lowered HIV-1 transmission risk in a breastfeeding population in Uganda compared with a short intrapartu/neonatal zidovudine regimen.
Journal ArticleDOI
A phase I / II study of the safety and pharmacokinetics of nevirapine in HIV-1-infected pregnant Ugandan women and their neonates (HIVNET 006).
Philippa Musoke,Laura Guay,Danstan Bagenda,Mark Mirochnick,Clemensia Nakabiito,Thomas Fleming,Terry Elliott,Scott Horton,Kevin Dransfield,Joseph W. Pav,Amal Murarka,Melissa Allen,Mary Glenn Fowler,Lynne M. Mofenson,David L. Hom,Francis Mmiro,J. Brooks Jackson +16 more
TL;DR: The administration of a single dose of nevirapine to women during labor and to their newborns at 72 h was well tolerated and showed potent antiretroviral activity in the women at 1 week after dosing without rebound above baseline 6 weeks after a single doses.
Journal ArticleDOI
Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow up of the HIVNET 012 randomized trial
J. Brooks Jackson,Philippa Musoke,Tom P. Fleming,Laura Guay,Danstan Bagenda,Melissa Allen,Clemensia Nakabiito,Joseph Sherman,Paul M. Bakaki,Maxensia Owor,Contance Ducar,Martina Deseyve,Anthony Mwatha,Lynda Emel,Corey Duefield,Mark Mirochnick,Mary Glenn Fowler,Lynne M. Mofenson,Paolo G. Miotti,Maria Gigllottl,Dorothy Bray,Francis Mmiro +21 more
TL;DR: Intrapartum/neonatal nevirapine appears to be a simple, inexpensive, and well-tolerated regimen for significantly reducing perinatal transmission of HIV-1 in less developed countries.
Journal ArticleDOI
Association of the Quick Sequential (Sepsis-Related) Organ Failure Assessment (qSOFA) Score With Excess Hospital Mortality in Adults With Suspected Infection in Low- and Middle-Income Countries.
Kristina E. Rudd,Christopher W. Seymour,Adam R. Aluisio,Marc E. Augustin,Danstan Bagenda,Abi Beane,Abi Beane,Jean Claude Byiringiro,Chung-Chou H. Chang,L. Nathalie Colas,Nicholas P. J. Day,Nicholas P. J. Day,A. Pubudu De Silva,Arjen M. Dondorp,Arjen M. Dondorp,Martin W. Dünser,M. Abul Faiz,Donald S. Grant,Rashan Haniffa,Nguyen Van Hao,Jason Kennedy,Adam C. Levine,Direk Limmathurotsakul,Direk Limmathurotsakul,Sanjib Mohanty,François Nosten,François Nosten,Alfred Papali,Andrew J. Patterson,John S. Schieffelin,Jeffrey G. Shaffer,Duong Bich Thuy,C. Louise Thwaites,Olivier Urayeneza,Nicholas J. White,Nicholas J. White,T. Eoin West,Derek C. Angus +37 more
TL;DR: When assessed among hospitalized adults with suspected infection in 9 LMIC cohorts, the qSOFA score identified infected patients at risk of death beyond that explained by baseline factors, however, the predictive validity varied among cohorts and settings, and further research is needed to better understand potential generalizability.