C
Constantin E. Sekeris
Researcher at University of Marburg
Publications - 73
Citations - 2138
Constantin E. Sekeris is an academic researcher from University of Marburg. The author has contributed to research in topics: RNA & RNA polymerase. The author has an hindex of 26, co-authored 73 publications receiving 2122 citations.
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Journal ArticleDOI
Functional testosterone receptors in plasma membranes of T cells
W. Peter M. Benten,Michèle Lieberherr,Günter Giese,Christian Wrehlke,Olaf Stamm,Constantin E. Sekeris,Horst Mossmann,Frank Wunderlich +7 more
TL;DR: The testosterone responsiveness of murine splenic T cells in vitro as well as the presence of unconventional cell surface receptors for testosterone and classical intracellular AR are demonstrated, suggesting that the classical AR present in splenicT cells are not active in the genomic pathway.
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Testosterone induces Ca2+ influx via non‐genomic surface receptors in activated T cells
TL;DR: Data indicate a novel mode of direct action of testosterone on T cells which is not mediated through the classical androgen receptor response, but through unconventional plasma membrane receptors.
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Translation of mRNA from rat-liver polysomes into tyrosine aminotransferase and tryptophan oxygenase in a protein-synthesizing system from wheat germ. Effects of cortisol on the translatable levels of mRNA for these two enzymes.
TL;DR: The amount of translatable tyrosine aminotransferase mRNA and tryptophan oxygenase mRNA increases after administration of hydrocortisone to adrenalectomized rats, and the enzyme activity curves are parallel to the mRNA curves.
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On the mechanism of hormone action. XV. Subcellular distribution and binding of (1,2-3H)cortisol in rat liver.
TL;DR: Radioactivity in rat liver was investigated 20 min after intraperitoneal injection of 20 and 200 μC of [3H]cortisol and was found to be weakly associated with a macromolecular fraction in a form resistant to nucleases but sensitive to pronase, trypsin and neuraminidase.
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On the mechanism of hormone action: XIII. Stimulating effects of ecdysone, juvenile hormone and ions on RNA synthesis in fat body cell nuclei from Calliphora erythrocephala isolated by a filtration technique☆
TL;DR: The effects of ecdysone and juvenile hormone alone on the RNA synthesis could be inhibited by incubating the nuclei with both hormones together, and this effect seemed to be independent of the sodium stimulation.