C
Constantinos Yiangou
Researcher at Queen Alexandra Hospital
Publications - 17
Citations - 1849
Constantinos Yiangou is an academic researcher from Queen Alexandra Hospital. The author has contributed to research in topics: Breast cancer & Sentinel node. The author has an hindex of 8, co-authored 17 publications receiving 1696 citations.
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Journal ArticleDOI
Randomized Multicenter Trial of Sentinel Node Biopsy Versus Standard Axillary Treatment in Operable Breast Cancer: The ALMANAC Trial
Robert E. Mansel,Lesley Fallowfield,Mark Kissin,Amit Goyal,Robert G. Newcombe,J Michael Dixon,Constantinos Yiangou,Kieran Horgan,Nigel J Bundred,I. Monypenny,David England,Mark Sibbering,Tholkifl I. Abdullah,Lester Barr,Utheshtra Chetty,Dudley H. Sinnett,Anne Fleissig,Dayalan Clarke,Peter J. Ell +18 more
TL;DR: Sentinel lymph node biopsy is associated with reduced arm morbidity and better quality of life than standard axillary treatment and should be the treatment of choice for patients who have early-stage breast cancer with clinically negative nodes.
Journal ArticleDOI
Cancer cell adaptation to chemotherapy.
Federica Di Nicolantonio,Stuart Mercer,Louise A. Knight,Francis G Gabriel,Pauline A. Whitehouse,Sanjay Sharma,Augusta Fernando,Sharon Glaysher,Silvana Di Palma,Penny Johnson,Shaw Somers,Simon Toh,Bernard Higgins,Alan Lamont,Tim J. Gulliford,Jeremy Hurren,Constantinos Yiangou,Ian A. Cree +17 more
TL;DR: It is suggested that up-regulation of resistance genes or down-regulation in target genes may occur rapidly in human solid tumors, within days of the start of treatment, and that similar changes are present in pre- and post-chemotherapy biopsy material.
Journal ArticleDOI
Sentinel lymph node biopsy in male breast cancer patients.
Amit Goyal,Kieran Horgan,Mark Kissin,Constantinos Yiangou,Mark Sibbering,Mark Lansdown,Robert G. Newcombe,Robert E. Mansel +7 more
TL;DR: SLN biopsy accurately staged the axilla in male breast cancer patients and should be considered for axillary staging in male Breast cancer patients with clinically negative axillae.
Journal ArticleDOI
Breast cancer follow up: A randomised controlled trial comparing point of need access versus routine 6-monthly clinical review
TL;DR: After 2 years following the diagnosis of breast cancer there is no evidence to support the view that regular clinical review improves psychological morbidity or quality of life, and point of need access is acceptable to the majority of patients.
Journal ArticleDOI
Observational and cost analysis of the implementation of breast cancer sentinel node intraoperative molecular diagnosis.
Ramsey I. Cutress,A. McDowell,Francis G Gabriel,J. Gill,Margaret J. Jeffrey,Avi Agrawal,M. Wise,James Raftery,Ian A. Cree,Constantinos Yiangou +9 more
TL;DR: Intraoperative assessment of SLNs in breast cancer using a molecular assay is a safe, acceptable and accurate technique that allows a reduction in the frequency of delayed axillary clearance surgery.