C
Cynthia J. Meininger
Researcher at Texas A&M University
Publications - 123
Citations - 11763
Cynthia J. Meininger is an academic researcher from Texas A&M University. The author has contributed to research in topics: Arginine & Nitric oxide. The author has an hindex of 53, co-authored 122 publications receiving 10819 citations. Previous affiliations of Cynthia J. Meininger include Oklahoma State University–Stillwater & Veterans Health Administration.
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Journal ArticleDOI
Presence of glutamine:fructose-6-phosphate amidotransferase for glucosamine-6-phosphate synthesis in endothelial cells: effects of hyperglycaemia and glutamine.
TL;DR: The results show the presence of glutamine:fructose-6-phosphate amidotransferase for de novo glucosamine synthesis in endothelial cells and the modulation of this pathway by hyperglycaemia and glutamine.
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Safety of dietary supplementation with arginine in adult humans
Catherine J. McNeal,Cynthia J. Meininger,Colin D. Wilborn,Carmen D. Tekwe,Guoyao Wu,Guoyao Wu +5 more
TL;DR: A randomized, placebo-controlled, clinical trial to evaluate the safety and tolerability of oral Arg in overweight or obese but otherwise healthy adults and concludes that a long-term safe level of dietary Arg supplementation is at least 30 g/day in adult humans.
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Internalization of eNOS and NO delivery to subcellular targets determine agonist-induced hyperpermeability
Fabiola A. Sánchez,Roshniben Rana,David D. Kim,Toru Iwahashi,Ruifang Zheng,Brajesh K. Lal,Donna M. Gordon,Cynthia J. Meininger,Walter N. Durán +8 more
TL;DR: It is demonstrated that eNOS internalization is required for agonist-induced hyperpermeability, and it is suggested that a mechanism by which eN OS is activated by phosphorylation at the plasma membrane and its endocytosis is required to deliver NO to subcellular targets to cause hyperPermeability.
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S-nitrosation of β-catenin and p120 catenin: a novel regulatory mechanism in endothelial hyperpermeability
Natalie Marín,Patricia Zamorano,Rodrigo Carrasco,Patricio E. Mujica,Francisco G. González,Francisco G. González,Claudia Quezada,Cynthia J. Meininger,Mauricio P. Boric,Walter N. Durán,Fabiola A. Sánchez +10 more
TL;DR: It is demonstrated that agonist-induced SNO contributes to junctional membrane protein changes that enhance endothelial permeability, whereas inhibition of the cGMP pathway had no effect.
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Tetrahydrobiopterin levels regulate endothelial cell proliferation.
TL;DR: It is suggested that BH 4 levels regulate proliferation of normal EC and that a BH4 deficiency impairs NO-dependent proliferation of BBd EC.