C
Cynthia Pan
Researcher at Regeneron
Publications - 8
Citations - 1467
Cynthia Pan is an academic researcher from Regeneron. The author has contributed to research in topics: Viral load & Medicine. The author has an hindex of 4, co-authored 6 publications receiving 614 citations.
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Journal ArticleDOI
REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19.
David M. Weinreich,Sumathi Sivapalasingam,Thomas Norton,Shazia Ali,Haitao Gao,Rafia Bhore,Bret J Musser,Yuhwen Soo,Diana Rofail,Joseph Im,Christina Perry,Cynthia Pan,Romana Hosain,Adnan Mahmood,John D. Davis,Kenneth C. Turner,Andrea T. Hooper,Jennifer D. Hamilton,Alina Baum,Christos A. Kyratsous,Yunji Kim,Amanda Cook,Wendy Kampman,Anita Kohli,Yessica Sachdeva,Ximena Graber,Bari Kowal,Thomas DiCioccio,Neil Stahl,Leah Lipsich,Ned Braunstein,Gary Herman,George D. Yancopoulos +32 more
TL;DR: In this interim analysis, the REGN-COV2 antibody cocktail reduced viral load, with a greater effect in patients whose immune response had not yet been initiated or who had a high viral load at baseline.
Posted ContentDOI
REGEN-COV Antibody Cocktail Clinical Outcomes Study in Covid-19 Outpatients
David M. Weinreich,Sumathi Sivapalasingam,Thomas Norton,Shazia Ali,Haitao Gao,Rafia Bhore,Jing Xiao,Andrea T. Hooper,Jennifer D. Hamilton,Bret J Musser,Diana Rofail,Mohamed Hussein,Joseph Im,Dominique Y Atmodjo,Christina Perry,Cynthia Pan,Adnan Mahmood,Romana Hosain,John D. Davis,Kenneth C. Turner,Alina Baum,Christos A. Kyratsous,Yunji Kim,Amanda Cook,Wendy Kampman,Lilia Roque-Guerrero,Gerard Acloque,Hessam Aazami,Kevin Cannon,J. Abraham Simon-Campos,Joseph A. Bocchini,Bari Kowal,Thomas DiCioccio,Yuhwen Soo,Neil Stahl,Leah Lipsich,Ned Braunstein,Gary Herman,George D. Yancopoulos,Trial Investigators +39 more
TL;DR: Regen-COV has been shown to significantly reduce Covid-19-related hospitalization or all-cause death, rapidly resolved symptoms, and reduced viral load as discussed by the authors.
Posted ContentDOI
REGEN-COV Antibody Cocktail in Outpatients with Covid-19
David M. Weinreich,Sumathi Sivapalasingam,Thomas Norton,Shazia Ali,Haitao Gao,Rafia Bhore,Andrea T. Hooper,Jennifer D. Hamilton,Bret J Musser,Yuhwen Soo,Diana Rofail,Joseph Im,Christina Perry,Cynthia Pan,Romana Hosain,Adnan Mahmood,John D. Davis,Kenneth C. Turner,Alina Baum,Christos A. Kyratsous,Yunji Kim,Amanda Cook,Wendy Kampman,Ximena Graber,Gerard Acloque,Yessica Sachdeva,Joseph A. Bocchini,Anita Kohli,Bari Kowal,Thomas DiCioccio,Neil Stahl,Leah Lipsich,Ned Braunstein,Gary Herman,George D. Yancopoulos +34 more
TL;DR: REGEN-COV treatment of outpatients significantly reduced SARS-CoV-2 viral load and Covid-19-related medically-attended visits and safety was similar across groups.
Journal ArticleDOI
REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19.
David M. Weinreich,Sumathi Sivapalasingam,Thomas T. Norton,Shazia Ali,Haitao Gao,Rafia Bhore,Jing Xiao,Andrea T. Hooper,Jennifer D. Hamilton,Bret J. Musser,Diana Rofail,Mohamed Hussein,Joseph Im,Dominique Y Atmodjo,Christina Perry,Cynthia Pan,Adnan Mahmood,Romana Hosain,John D. Davis,Kenneth C. Turner,Alina Baum,Christos A. Kyratsous,Yunji Kim,Amanda Cook,Wendy Kampman,Lilia Roque-Guerrero,Gerard Acloque,Hessam Aazami,Kevin Cannon,J. Abraham Simon-Campos,Joseph A. Bocchini,Bari Kowal,A. Thomas DiCioccio,Yuhwen Soo,Gregory P. Geba,Neil Stahl,Leah Lipsich,Ned Braunstein,G. Herman,George D. Yancopoulos +39 more
TL;DR: In the phase 3 portion of an adaptive trial, the authors randomly assigned outpatients with Covid-19 and risk factors for severe disease to receive various doses of intravenous REGEN-COV or placebo.
Posted ContentDOI
REGEN-COV® for Treatment of Hospitalized Patients with Covid-19
Selin Somersan-Karakaya,Eleftherios Mylonakis,Vidya Menon,Jason C. Wells,Shazia Ali,Sumathi Sivapalasingam,Yiping Sun,Rafia Bhore,Jingning Mei,Jutta Miller,Lisa Cupelli,Andrea T. Hooper,Jennifer D. Hamilton,Cynthia Pan,Viet Pham,Yuming Zhao,Romana Hosain,Adnan Mahmood,John D. Davis,Kenneth C. Turner,Yunji Kim,Amanda Cook,Bari Kowal,Yuhwen Soo,A. Thomas DiCioccio,Gregory P. Geba,Neil Stahl,Leah Lipsich,Ned Braunstein,Gary Herman,George D. Yancopoulos,David M. Weinreich,Hospitalized Trial Team +32 more
TL;DR: In this article, a double-blind placebo-controlled trial was conducted to evaluate the effect of anti-spike monoclonal antibody therapy on the risk of death or mechanical ventilation as well as all-cause mortality in the overall population.