Leah Lipsich

TL;DR: In this interim analysis, the REGN-COV2 antibody cocktail reduced viral load, with a greater effect in patients whose immune response had not yet been initiated or who had a high viral load at baseline.

TL;DR: The combination of the monoclonal antibodies casirivimab and imdevimab has been shown to markedly reduce the risk of hospitalization or... as discussed by the authors, which is known as REGN-COV2.

TL;DR: It is suggested that simply augmenting the blocking IgG/IgE ratio may reverse allergy, and the administration of two cat allergen-specific IgGs reduces allergic responses in mouse models and helps ameliorate clinical symptoms in a phase 1b clinical trial.

TL;DR: In this paper, the sequence diversity of the spike protein and monitored emergence of virus variants in SARS-CoV-2 isolates found in COVID-19 patients treated with the two-antibody combination REGEN-COV, as well as in preclinical in vitro studies using single, dual, or triple antibody combinations.

TL;DR: A single dose of a cocktail of the 3 antibodies protected nonhuman primates (NHPs) from EBOV disease even after disease symptoms were apparent, and demonstrates high-level postexposure protection from lethal E BOV disease in NHPs.