D. Arnoux

TL;DR: Examination of morphological, immunological, and functional characteristics of MPs derived from human umbilical vein endothelial cells stimulated by TNF provides evidence that endothelial-derived MPs are detectable in normal human blood and are increased in patients with a coagulation abnormality characterized by the presence of lupus anticoagulant.

TL;DR: Results showed that a wide vesiculation process, resulting from activation or apoptosis of several cell types, occurs in diabetes, however, diabetic patients differ by the procoagulant activity and the cellular origin of microparticles.

TL;DR: Ex vivo and in vitro observations indicate that generation of EMP in APS and SLE patients results from an autoimmune process involving aPL, which may represent a new pathogenic mechanism for the thrombotic complications of this disease.

TL;DR: It is demonstrated here that human endothelial cells can be directly isolated and identified in circulating blood by means of an endothelial cell specific monoclonal antibody, S-Endo1, coupled to micromagnetic beads, and may be useful in determining endothelium cell injury in vascular disorders.

TL;DR: A new whole blood immunocytometric assay based on a new monoclonal antibody S-Endo 1 MAb, made against human umbilical vein endothelial cells (HUVEC), which may be useful in determining the levels of circulating endothelium cells in vascular disorders.