L
Laurence Camoin
Researcher at Aix-Marseille University
Publications - 26
Citations - 2014
Laurence Camoin is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Acute coronary syndrome & Clopidogrel. The author has an hindex of 14, co-authored 22 publications receiving 1863 citations. Previous affiliations of Laurence Camoin include French Institute of Health and Medical Research.
Papers
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Journal ArticleDOI
In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant
Valery Combes,Anne Christine Simon,Georges E. Grau,D. Arnoux,Laurence Camoin,Florence Sabatier,Murielle Mutin,Marielle Sanmarco,José Sampol,Françoise Dignat-George +9 more
TL;DR: Examination of morphological, immunological, and functional characteristics of MPs derived from human umbilical vein endothelial cells stimulated by TNF provides evidence that endothelial-derived MPs are detectable in normal human blood and are increased in patients with a coagulation abnormality characterized by the presence of lupus anticoagulant.
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Interaction of endothelial microparticles with monocytic cells in vitro induces tissue factor-dependent procoagulant activity.
Florence Sabatier,Veronique Roux,Francine Anfosso,Laurence Camoin,José Sampol,Françoise Dignat-George +5 more
TL;DR: It is demonstrated that EMPs interact with THP-1 cells in vitro and stimulate TF-mediated procoagulant activity that is partially dependent on the interaction of ICAM-1 on EMP and its counterreceptor, beta2 integrins, on THP -1 cells.
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ADP-induced platelet aggregation and platelet reactivity index VASP are good predictive markers for clinical outcomes in non-ST elevation acute coronary syndrome.
Corinne Frere,Thomas Cuisset,Jacques Quilici,Laurence Camoin,Joseph Carvajal,Pierre-Emmanuel Morange,Marc Lambert,Irène Juhan-Vague,Jean-Louis Bonnet,Marie-Christine Alessi +9 more
TL;DR: In patients with NSTE ACS undergoing PCI, ADP-Ag and PRI VASP identify low responders to clopidogrel with an increased risk of recurrent ischemic events with respective cut-off values of 70% and 53%.
Journal ArticleDOI
Circulating microparticles: a marker of procoagulant state in normal pregnancy and pregnancy complicated by preeclampsia or intrauterine growth restriction
Florence Bretelle,Florence Sabatier,Dominique Desprez,Laurence Camoin,Lelia Grunebaum,Combes,Claude D'Ercole,Françoise Dignat-George +7 more
TL;DR: It is evidenced that microparticles constitute a cellular marker of a proinflammatory and procoagulant responses in normal pregnancy and in pregnancies with vascular complications, circulating MP with procogulant potential may be part of the exacerbation of these responses.
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Role of the T744C polymorphism of the P2Y12 gene on platelet response to a 600-mg loading dose of clopidogrel in 597 patients with non-ST-segment elevation acute coronary syndrome
Thomas Cuisset,Corinne Frere,Jacques Quilici,Pierre-Emmanuel Morange,Noémie Saut,Marc Lambert,Laurence Camoin,Irene Juhan Vague,Jean-Louis Bonnet,Marie-Christine Alessi +9 more
TL;DR: This study did not show any influence of the T744C polymorphism of the P2Y12 receptor gene on clopidogrel response assessed by ADP-Ag, PRI VASP or P-selectin expression in NSTE ACS patients.