D
D. Assisi
Publications - 17
Citations - 313
D. Assisi is an academic researcher. The author has contributed to research in topics: Medicine & Colorectal cancer. The author has an hindex of 6, co-authored 13 publications receiving 277 citations.
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Journal Article
The Lynch syndrome
TL;DR: Endoscopic screening has been demonstrated to reduce incidence of colorectal malignancies in Lynch syndrome, and genetic test allows identifying the state of mutation carriers and selects the patients to submit to screening.
Journal Article
Activation of c-myc and c-myb proto-oncogenes is associated with decreased apoptosis in tumor colon progression
C. Greco,Alvino S,Simonetta Buglioni,D. Assisi,R. Lapenta,A. Grassi,Vittoria Stigliano,Marcella Mottolese,V. Casale +8 more
TL;DR: Results indicate that failure of the normal apoptotic process together with de-regulation of c-myc and c- myb proto-oncogenes might promote the development of colorectal tumors.
Journal ArticleDOI
Survival of hereditary non-polyposis colorectal cancer patients compared with sporadic colorectal cancer patients.
Vittoria Stigliano,D. Assisi,Maurizio Cosimelli,Raffaele Palmirotta,Diana Giannarelli,Marcella Mottolese,Lupe Sanchez Mete,R. Mancini,V. Casale +8 more
TL;DR: Overall survival of colorectal cancer in patients with HNPCC is better than sporadic CRC patients, and the different outcome probably relates to the specific tumorigenesis involving DNA mismatch repair dysfunction.
Journal ArticleDOI
Cell surface overexpression of Galectin-3 and the presence of its ligand 90k in the blood plasma as determinants in colon neoplastic lesions
C. Greco,Rosa Vona,Maurizio Cosimelli,Paola Matarrese,Elisabetta Straface,Patrizia Scordati,Diana Giannarelli,V. Casale,D. Assisi,Marcella Mottolese,Anna Moles,Walter Malorni +11 more
TL;DR: Results clearly indicate that the evaluation of Gal-3 expression (and of its ligand, 90k) can be of interest in the characterization of nonmalignant and malignant colon cancers.
Journal Article
Current trends in screening and secondary prevention of colorectal cancer.
TL;DR: The results of different screening strategies for average risk patients (FOBT, anamnestic risk questionnaire, sigmoidoscopy, colonoscopy and virtual Colonoscopy) and the surveillance protocols applicable to high-risk patients, particularly for hereditary syndromes such as HNPCC and FAP are summarized.