D
D. Eugene Redmond
Researcher at Yale University
Publications - 92
Citations - 7149
D. Eugene Redmond is an academic researcher from Yale University. The author has contributed to research in topics: MPTP & Dopamine. The author has an hindex of 42, co-authored 91 publications receiving 6900 citations. Previous affiliations of D. Eugene Redmond include Rush Medical College & University of Delaware.
Papers
More filters
Journal ArticleDOI
Clonidine blocks acute opiate-withdrawal symptoms
TL;DR: The data suggest that opiate withdrawal is due to increased neuronal activity in areas such as the locus coeruleus which are regulated by both alpha-2 adrenergic and opiate receptors.
Journal ArticleDOI
Unilateral Transplantation of Human Fetal Mesencephalic Tissue into the Caudate Nucleus of Patients with Parkinson's Disease
Dennis D. Spencer,Richard J. Robbins,Frederick Naftolin,Kenneth Marek,Timothy Vollmer,Csaba Leranth,Robert H. Roth,Lawrence H. Price,Albert Gjedde,Benjamin S. Bunney,Kimberlee J. Sass,John D. Elsworth,E. Leon Kier,Robert W. Makuch,Paul B. Hoffer,D. Eugene Redmond +15 more
TL;DR: Although the case patients with severe Parkinson's disease continued to be disabled by their disease, unilateral intracaudate grafts of fetal tissue containing dopamine diminished the symptoms and signs of parkinsonism during 18 months of evaluation.
Journal ArticleDOI
Enduring Cognitive Deficits and Cortical Dopamine Dysfunction in Monkeys After Long-Term Administration of Phencyclidine
J. David Jentsch,D. Eugene Redmond,John D. Elsworth,Jane R. Taylor,Kenneth D. Youngren,Robert H. Roth +5 more
TL;DR: The data suggest that repeated administration of phencyclidine in monkeys may be useful for studying psychiatric disorders associated with cognitive dysfunction and dopamine hypofunction in the prefrontal cortex, particularly schizophrenia.
Journal ArticleDOI
Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells
D. Eugene Redmond,Kimberly B. Bjugstad,Yang D. Teng,Vaclav Ourednik,Jitka Ourednik,Dustin R. Wakeman,Xuejun H. Parsons,Rodolfo Gonzalez,Barbara C. Blanchard,Seung U. Kim,Zezong Gu,Stuart A. Lipton,Eleni A. Markakis,Robert H. Roth,John D. Elsworth,John R. Sladek,Richard L. Sidman,Evan Y. Snyder +17 more
TL;DR: It is proposed that multiple modes of reciprocal interaction between exogenous hNSCs and the pathological host milieu underlie the functional improvement observed in this model of PD.
Journal ArticleDOI
Yohimbine induced anxiety and increased noradrenergic function in humans: effects of diazepam and clonidine.
TL;DR: Findings indicate that noradrenergic hyperactivity may be a factor in the production of some anxiety states and the anti-anxiety effects of clonidine appear to result from its actions on receptors which decrease nor adrenergic activity.