D
D. R. Crapper-MacLachlan
Researcher at University of Toronto
Publications - 1
Citations - 3551
D. R. Crapper-MacLachlan is an academic researcher from University of Toronto. The author has contributed to research in topics: SORL1 & Allele frequency. The author has an hindex of 1, co-authored 1 publications receiving 3419 citations.
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Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease.
Ann M. Saunders,Warren J. Strittmatter,Donald E. Schmechel,P. St. George-Hyslop,Margaret A. Pericak-Vance,S. H. Joo,B.L. Rosi,James F. Gusella,D. R. Crapper-MacLachlan,Mark J. Alberts,Christine M. Hulette,Barbara J. Crain,Dmitry Goldgaber,A. D. Roses +13 more
TL;DR: Data support the involvement of ApoE ϵ4 in the pathogenesis of late-onset familial and sporadic AD and suggest it may operate as a susceptibility gene (risk factor) for the clinical expression of AD.