D.R. Gardner

TL;DR: It is concluded that the stretch-sensitive kinetic component of theHeart ventricle cells of Lymnaea stagnalis contain a stretch-activated K + channel which exhibits two open states and three closed states.

TL;DR: The relationship between the membrane potential, the external potassium concentration and the channel currents, when compared with results obtained from whole cell recording, suggests that this channel could mediate a large part of the cell's resting conductance.

TL;DR: Both sodium and barium currents were initiated when the peptides were applied to the cell outside of the patch pipette indicating that a secondary messenger is likely to be involved in the FMRFamide response.

TL;DR: The membrane of the heart ventricle muscle cells appears to be permeable to both potassium and chloride, as changes in the extracellular concentration of either of these ions resulted in a change in the membrane potential.

TL;DR: The cell-attached, patch-clamp technique was used to investigate the modulatory role of the neuropeptide SEQPDVDDYLRDVVLQSEEPLY on FMRFamide-activated Ca2+ channels in isolated Lymnaea heart ventricular cells and suggested that corelease of the two peptides might act together to regulate the level of Ca2-activated channel activity within a defined range.