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D Y Mason

Researcher at John Radcliffe Hospital

Publications -  140
Citations -  15856

D Y Mason is an academic researcher from John Radcliffe Hospital. The author has contributed to research in topics: Antigen & Monoclonal antibody. The author has an hindex of 59, co-authored 140 publications receiving 15671 citations. Previous affiliations of D Y Mason include Churchill Hospital.

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Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).

TL;DR: The APAAP technique was found particularly suitable for labeling cell smears and for detecting low numbers of antigen-bearing cells in a specimen and could be used in conjunction with immunoperoxidase methods for double immunoenzymatic staining.
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The expression of the Hodgkin's disease associated antigen Ki-1 in reactive and neoplastic lymphoid tissue: evidence that Reed-Sternberg cells and histiocytic malignancies are derived from activated lymphoid cells.

TL;DR: Results obtained indicate that Ki-1 antigen is an inducible lymphoid-associated molecule that identifies a group of hitherto poorly characterized normal and neoplastic large lymphoid cells in Hodgkin's disease and Disorders in which only a minority of cells express Ki- 1 antigen probably represent lesions in whichonly some of the abnormal cells have transformed into an "activation state.
Journal Article

Expression of the bcl-2 oncogene protein is not specific for the 14;18 chromosomal translocation.

TL;DR: It is concluded that expression of bcl-2 protein is not a specific marker for lymphomas bearing the 14;18 chromosomal translocation and that the observations of other investigators may have reflected the inadequate sensitivity of their staining procedure.
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Transferrin receptors in human tissues: their distribution and possible clinical relevance.

TL;DR: The receptor was widely distributed in carcinomas, sarcomas and in samples from cases of Hodgkin's disease, suggesting that malignancy-associated expression of the receptor may play a role in the anaemia of advanced malignancies by competing with the bone marrow for serum iron.
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KP1: a new monoclonal antibody that detects a monocyte/macrophage associated antigen in routinely processed tissue sections.

TL;DR: A new monoclonal antibody, KP1, raised against a lysosomal fraction of human lung macrophages, recognises a fixation-resistant epitope in a wide variety of tissue macrophage-rich human tissue, and in granulocyte precursors.