D Y Mason

TL;DR: The value of antibodies Ki-1 and Ber-H2 in distinguishing between lymphomatoid papulosis and other types of pre- or pseudo-malignant disorders are indicated and support the view that lymphom atoid papilosis, Hodgkin's disease and some types of non-Hodgkin's lymphoma constitute a spectrum of related disorders.

TL;DR: In high-grade NHLs mutations frequently occur outside the classic hot spot regions and staining for p53 is not predictive of the status of the gene, i.e. whether or not a mutation is present, therefore in order to document p53 involvement in lymphoid tumours it is necessary both to sequence at least the whole translated open reading frame of the genes and to show evidence of protein expression by immunostaining.

TL;DR: Ber-ACT8 as discussed by the authors is a new monoclonal antibody, which was developed using a newly established HTLV-1 positive T cell line as an immunogen, and it was used for the diagnosis of gut T cell-derived T cell lymphomas and other extranodal T-cell lymphomas.

TL;DR: As the number of diagnostically important monoclonal antibodies continues to increase, the use of freeze-dried paraffin sections should facilitate the introduction of immunohistological techniques for both routine histopathological diagnostic work and immunological research.

TL;DR: Bcl‐2 protein expression was studied in a series of 58 MALT lymphomas using a monoclonal antibody which recognises this protein in routinely processed paraffin embedded tissue to suggest that the good prognosis of Malt lymphomas may partly be explained by the fact that they maintain a normal pattern of bCl‐2 expression.