D
Dagmar Stöhr
Researcher at University of Ulm
Publications - 8
Citations - 110
Dagmar Stöhr is an academic researcher from University of Ulm. The author has contributed to research in topics: Human cytomegalovirus & Virus. The author has an hindex of 4, co-authored 7 publications receiving 83 citations.
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Journal ArticleDOI
A derivative of platelet-derived growth factor receptor alpha binds to the trimer of human cytomegalovirus and inhibits entry into fibroblasts and endothelial cells.
Cora Stegmann,Daniel Hochdorfer,Diana Lieber,Narmadha Subramanian,Dagmar Stöhr,Kerstin Laib Sampaio,Christian Sinzger +6 more
TL;DR: It is shown that soluble derivatives of the platelet-derived growth factor receptor alpha (PDGFR-alpha), a putative receptor of H CMV, can inhibit HCMV infection of various cell types and are hence promising candidates for the development of novel anti-HCMV therapies.
Journal ArticleDOI
Role of Envelope Glycoprotein Complexes in Cell-Associated Spread of Human Cytomegalovirus
Nina Weiler,Caroline Paal,Kerstin Adams,Christopher Calcaterra,Dina Fischer,Richard J. Stanton,Dagmar Stöhr,Kerstin Laib Sampaio,Christian Sinzger +8 more
TL;DR: In this paper, the role of trimer and pentameric gH/gL-complexes in cell-associated spread of human cytomegalovirus (HCMV) is investigated.
Journal ArticleDOI
A two-step screening approach for the identification of blood donors with highly and broadly neutralizing capacities against human cytomegalovirus.
Jessica Julia Falk,Martina Winkelmann,Hubert Schrezenmeier,Dagmar Stöhr,Christian Sinzger,Ramin Lotfi +5 more
TL;DR: To improve efficacy against HCMV infection, this work aimed at developing a high‐throughput screening method for identification of blood donors with highly and broadly neutralizing capacities.
Journal ArticleDOI
Identification of Elite Neutralizers With Broad and Potent Neutralizing Activity Against Human Cytomegalovirus (HCMV) in a Population of HCMV-Seropositive Blood Donors.
Jessica Julia Falk,Martina Winkelmann,Dagmar Stöhr,Mira Alt,Hubert Schrezenmeier,Hubert Schrezenmeier,Adalbert Krawczyk,Ramin Lotfi,Ramin Lotfi,Christian Sinzger +9 more
TL;DR: Plasma samples from elite-neutralizing donors can be considered to improve antibody-based treatment of HCMV infections because of their effect on individual virus particles during entry.
Journal ArticleDOI
Targeted mutagenesis on PDGFRα-Fc identifies amino acid modifications that allow efficient inhibition of HCMV infection while abolishing PDGF sequestration.
Svenja Feldmann,Immanuel Grimm,Dagmar Stöhr,Chiara Antonini,Chiara Antonini,Peter Lischka,Christian Sinzger,Cora Stegmann +7 more
TL;DR: In this article, a targeted mutagenesis approach was chosen to identify combinations of mutations in PDGFRα-Fc that prevent interference with PDGF-BB but maintain inhibition of HCMV.