J
Jing Fan
Researcher at National Institutes of Health
Publications - 10
Citations - 588
Jing Fan is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Nanomedicine & Drug delivery. The author has an hindex of 7, co-authored 10 publications receiving 438 citations. Previous affiliations of Jing Fan include Southeast University & Shenzhen University.
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Journal ArticleDOI
NIR‐Responsive On‐Demand Release of CO from Metal Carbonyl‐Caged Graphene Oxide Nanomedicine
Qianjun He,Qianjun He,Qianjun He,Dale O. Kiesewetter,Ying Qu,Xiao Fu,Jing Fan,Peng Huang,Yijing Liu,Guizhi Zhu,Yi Liu,Zhiyong Qian,Xiaoyuan Chen +12 more
TL;DR: On-demand release of carbon monoxide (CO) is realized through a novel near-infrared-responsive nanomedicine in favor of the enhancement of therapy efficacy and biosafety of CO therapy.
Journal ArticleDOI
Transformative Nanomedicine of an Amphiphilic Camptothecin Prodrug for Long Circulation and High Tumor Uptake in Cancer Therapy.
Fuwu Zhang,Guizhi Zhu,Orit Jacobson,Yi Liu,Yi Liu,Kai Chen,Guocan Yu,Qianqian Ni,Jing Fan,Zhen Yang,Frederick Xu,Xiao Fu,Zhe Wang,Ying Ma,Gang Niu,Xiaobin Zhao,Xiaoyuan Chen +16 more
TL;DR: A camptothecin prodrug that was well formulated in solution and rapidly transformed into long-circulating nanocomplexes in vivo for highly efficient drug delivery and effective cancer therapy is reported.
Journal ArticleDOI
A novel self-assembled sandwich nanomedicine for NIR-responsive release of NO
Jing Fan,Jing Fan,Nongyue He,Qianjun He,Yi Liu,Ying Ma,Xiao Fu,Yijing Liu,Peng Huang,Xiaoyuan Chen +9 more
TL;DR: The intracellular NIR-responsive release of NO from the GO-BNN6 nanomedicine causes a remarkable anti-cancer effect and is easily triggered and effectively controlled by adjusting the switching, irradiation time and power density of NIR laser.
Journal ArticleDOI
Light-Responsive Biodegradable Nanomedicine Overcomes Multidrug Resistance via NO-Enhanced Chemosensitization.
Jing Fan,Qianjun He,Yi Liu,Fuwu Zhang,Xiangyu Yang,Xiangyu Yang,Zhe Wang,Nan Lu,Wenpei Fan,Wenpei Fan,Lisen Lin,Gang Niu,Nongyue He,Jibin Song,Xiaoyuan Chen +14 more
TL;DR: A nitric oxide (NO) gas-enhanced chemosensitization strategy is proposed to overcome MDR by construction of a biodegradable nanomedicine formula based on BNN6/DOX coloaded monomethoxy(polyethylene glycol)-poly(lactic-co-glycolic acid) (mPEG-PLGA).
Journal ArticleDOI
Hierarchical Assembly of Bioactive Amphiphilic Molecule Pairs into Supramolecular Nanofibril Self-Supportive Scaffolds for Stem Cell Differentiation.
Zhe Wang,Fuwu Zhang,Zhantong Wang,Yijing Liu,Xiao Fu,Albert J. Jin,Bryant C. Yung,Wei Chen,Jing Fan,Xiangyu Yang,Gang Niu,Xiaoyuan Chen +11 more
TL;DR: This study is a successful attempt to entirely use bioactive molecules for bottom-up self-assembly of new biomaterials mimicking the ECM to directly impact cell behaviors and provides a new avenue in biomaterial design to advance tissue engineering and cell delivery.