D
Dan Chateau
Researcher at University of Manitoba
Publications - 170
Citations - 5486
Dan Chateau is an academic researcher from University of Manitoba. The author has contributed to research in topics: Population & Medicine. The author has an hindex of 33, co-authored 145 publications receiving 4599 citations. Previous affiliations of Dan Chateau include University of California, San Diego & University of Western Ontario.
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Journal ArticleDOI
Initiation of Inappropriate Antimicrobial Therapy Results in a Fivefold Reduction of Survival in Human Septic Shock
Anand Kumar,Anand Kumar,Paul Ellis,Yaseen M. Arabi,Dan Roberts,Bruce Light,Joseph E. Parrillo,Peter Dodek,Gordon Wood,Aseem Kumar,David Simon,Cheryl Peters,Muhammad Ahsan,Dan Chateau +13 more
TL;DR: Efforts to increase the frequency of the appropriateness of initial antimicrobial therapy must be central to efforts to reduce the mortality of patients with septic shock.
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A survival benefit of combination antibiotic therapy for serious infections associated with sepsis and septic shock is contingent only on the risk of death: a meta-analytic/meta-regression study.
TL;DR: Combination antibiotic therapy improves survival and clinical response of high-risk, life-threatening infections, particularly those associated with septic shock but may be detrimental to low-risk patients.
Journal ArticleDOI
Frequent Users of Emergency Departments: Developing Standard Definitions and Defining Prominent Risk Factors
Malcolm Doupe,Wes Palatnick,Suzanne Day,Dan Chateau,Ruth-Ann Soodeen,Charles Burchill,Shelley Derksen +6 more
TL;DR: Although substance abuse is prominent in both groups, only highly frequent users seem to visit EDs in place of other health care services, suggesting that these former patients use EDs as a main source of care.
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A matched cohort study of postoperative outcomes in obstructive sleep apnea: could preoperative diagnosis and treatment prevent complications?
TL;DR: Diagnosis of OSA and prescription of continuous positive airway pressure therapy were associated with a reduction in postoperative cardiovascular complications, and could be used to justify and inform large efficacy trials of perioperative continuous positiveAirway Pressure therapy in OSA patients.
Journal ArticleDOI
Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis
Kristian B. Filion,Dan Chateau,Laura E. Targownik,Andrea S. Gershon,Madeleine Durand,Hala Tamim,Gary F. Teare,Pietro Ravani,Pierre Ernst,Colin R. Dormuth +9 more
TL;DR: This study does not support the proposition of a pharmacological effect of gastric acid suppressors on the risk of HCAP and formed eight restricted cohorts of new users of NSAIDs, aged ≥40 years, using a common protocol in eight databases.