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Dan L. McElroy
Researcher at University of Saskatchewan
Publications - 10
Citations - 36
Dan L. McElroy is an academic researcher from University of Saskatchewan. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 2, co-authored 5 publications receiving 11 citations.
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Journal ArticleDOI
Dissociable changes in spike and wave discharges following exposure to injected cannabinoids and smoked cannabis in Genetic Absence Epilepsy Rats from Strasbourg.
Andrew J. Roebuck,Andrew J. Roebuck,Quentin Greba,Timothy J. Onofrychuk,Dan L. McElroy,Thaísa M. Sandini,Ayat Zagzoog,Jonathan J. Simone,Stuart M. Cain,Terrance P. Snutch,Robert B. Laprairie,Robert B. Laprairie,John G. Howland +12 more
TL;DR: In this article, the effects of Δ9 -tetrahydrocannabinol (THC) and cannabidiol (CBD) exposure to smoke from two different chemovars of cannabis were tested in GAERS.
Journal ArticleDOI
Effects of the cannabinoid receptor 1 positive allosteric modulator GAT211 and acute MK-801 on visual attention and impulsivity in rats assessed using the five-choice serial reaction time task
Timothy J. Onofrychuk,Shuang Cai,Dan L. McElroy,Andrew J. Roebuck,Quentin Greba,Sumanta Garai,Ganesh A. Thakur,Robert B. Laprairie,John G. Howland +8 more
TL;DR: The dramatic effects of acute MK-801 treatment on behavioral measures of attention and impulsivity are confirmed and continued investigation of CB1R positive allosteric modulators as potential treatments for the cognitive symptoms of schizophrenia and related disorders should be pursued.
Journal ArticleDOI
Antipsychotic potential of the type 1 cannabinoid receptor positive allosteric modulator GAT211: preclinical in vitro and in vivo studies
Dan L. McElroy,Andrew J. Roebuck,Gavin A. Scott,Quentin Greba,Sumanta Garai,Eileen M. Denovan-Wright,Ganesh A. Thakur,Robert B. Laprairie,Robert B. Laprairie,John G. Howland +9 more
TL;DR: In this paper, the effects of GAT211 and THC on cellular signaling were compared in Neuro2a cells, and behavioral effects on altered locomotor activity and prepulse inhibition of the acoustic startle response caused by acute MK-801 treatment were assessed in male, Long Evans rats.
Journal ArticleDOI
The effects of acute Cannabis smoke or Δ9-THC injections on the trial-unique, nonmatching-to-location and five-choice serial reaction time tasks in male Long-Evans rats
Ilne L. Barnard,Timothy J. Onofrychuk,Thaísa Meira Sandini,Dan L. McElroy,Ayat Zagzoog,Andrew J. Roebuck,Faith V. Austin-Scott,Robert B. Laprairie,John G. Howland +8 more
TL;DR: In this article , the effects of acute smoke exposure, nor injected THC, impacted attentional processes, impulsivity, perseverations, or response latencies in the 5-CSRTT.
Journal ArticleDOI
The type 1 cannabinoid receptor positive allosteric modulators GAT591 and GAT593 reduce spike-and-wave discharges in Genetic Absence Epilepsy Rats from Strasbourg
Dan L. McElroy,Andrew J. Roebuck,Quentin Greba,Sumanta Garai,Asher L. Brandt,Orhan Yilmaz,Stuart M. Cain,Terry P. Snutch,Ganesh A. Thakur,Robert B. Laprairie,John G. Howland +10 more
TL;DR: In this article , positive allosteric modulation of the type-1 cannabinoid receptor (CB1R) reduces the frequency and duration of SWDs in Genetic Absence Epilepsy Rats from Strasbourg (GAERS).