D
Dana Boyd
Researcher at Harvard University
Publications - 83
Citations - 10037
Dana Boyd is an academic researcher from Harvard University. The author has contributed to research in topics: Membrane protein & DsbA. The author has an hindex of 43, co-authored 82 publications receiving 9490 citations.
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Genes required for mycobacterial growth defined by high density mutagenesis
TL;DR: The use of transposon site hybridization (TraSH) is described to comprehensively identify the genes required by the causative agent, Mycobacterium tuberculosis, for optimal growth, suggesting that the minimal gene set required for survival varies greatly between organisms with different evolutionary histories.
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Comprehensive identification of conditionally essential genes in mycobacteria
TL;DR: A technique, transposon site hybridization (TraSH), which allows rapid functional characterization by identifying the complete set of genes required for growth under different conditions by combining high-density insertional mutagenesis with microarray mapping of pools of mutants.
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A Signaling Network Reciprocally Regulates Genes Associated with Acute Infection and Chronic Persistence in Pseudomonas aeruginosa
TL;DR: RetS is defined as a pleiotropic regulator of multiple virulence phenotypes that orchestrates genes required for acute infection and genes associated with chronic persistence.
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Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease.
TL;DR: Surprisingly, genes unique to all pandemic strains as well as genes specific to 7th pandemic El Tor and related O139 serogroup strains were identified and may encode gain-of-function traits specifically associated with displacement of the preexisting classical strains in South Asia.
Journal ArticleDOI
Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa
Matthew C. Wolfgang,Bridget R. Kulasekara,Xiaoyou Liang,Dana Boyd,Kai Wu,Qing Yang,C. Garrett Miyada,Stephen Lory +7 more
TL;DR: It is demonstrated that P. aeruginosa strains possess a highly conserved genome that encodes genes important for survival in numerous environments and allows it to cause a variety of human infections.