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Michelle Dziejman

Researcher at University of Rochester

Publications -  30
Citations -  4452

Michelle Dziejman is an academic researcher from University of Rochester. The author has contributed to research in topics: Vibrio cholerae & Virulence. The author has an hindex of 19, co-authored 30 publications receiving 4187 citations. Previous affiliations of Michelle Dziejman include Harvard University.

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IFN-γ-Inducible Protein 10 (IP-10; CXCL10)-Deficient Mice Reveal a Role for IP-10 in Effector T Cell Generation and Trafficking

TL;DR: A role for IP-10 is suggested in both effector T cell generation and trafficking in vivo, as seen in many Th1-type inflammatory diseases.
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Quorum-sensing regulators control virulence gene expression in Vibrio cholerae

TL;DR: It is shown that, in addition to the known components of the ToxR signaling circuit, quorum-sensing regulators are involved in regulation of V. cholerae virulence, and an infant mouse model found that a luxO mutant is severely defective in colonization of the small intestine.
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Comparative genomic analysis of Vibrio cholerae: genes that correlate with cholera endemic and pandemic disease.

TL;DR: Surprisingly, genes unique to all pandemic strains as well as genes specific to 7th pandemic El Tor and related O139 serogroup strains were identified and may encode gain-of-function traits specifically associated with displacement of the preexisting classical strains in South Asia.
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The T Cell-Specific CXC Chemokines IP-10, Mig, and I-TAC Are Expressed by Activated Human Bronchial Epithelial Cells

TL;DR: In this article, the effects of proinflammatory cytokines, including IFN-gamma, Th2-type cytokines (IL-4, IL-10, and IL-13), and dexamethasone were studied in normal human bronchial epithelial cells (NHBEC) and in two human respiratory epithelial cell lines, A549 and BEAS-2B.
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Determination of the transcriptome of Vibrio cholerae during intraintestinal growth and midexponential phase in vitro

TL;DR: The intestinal environment significantly enhanced expression of several virulence genes, including those involved in phenotypes such as motility, chemotaxis, intestinal colonization, and toxin production, relative to in vitro growth.