Dana Seidlova-Wuttke

TL;DR: It is proposed that CR BNO 1055 contains substances with SERM activity, i.e. with desired effects in the brain/hypothalamus, in the bone and in the vagina, but without exerting uterotrophic effects.

TL;DR: It is concluded that dopaminergic compounds present in Vitex agnus castus are clinically the important compounds which improve pre menstrual mastodynia and possibly also other symptoms of the premenstrual syndrome.

TL;DR: In general, several endocrine active compounds disrupt the endocrine feedback regulation of the thyroid axis, but each compound elicited its own spectrum of alterations, arguing for multiple targets of interference with the complex network of thyroid hormone action and metabolism.

TL;DR: The following question arises for the clinician: Why should soy or red clover products containing isoflavone be recommended, if the positive effects are only negligible but the adverse effects serious?

TL;DR: This approach involves novel in vitro or cell-based screening assays in order to assess thyroid hormone synthesis, transport, metabolism, and action as well as in vivo assays to measure thyroid hormone–regulated tissue-specific and developmental end points in animals.