D
Daniel Aum
Researcher at Brigham and Women's Hospital
Publications - 2
Citations - 188
Daniel Aum is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: In vivo & Prostate. The author has an hindex of 2, co-authored 2 publications receiving 98 citations.
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Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA.
Mohammad Ariful Islam,Yingjie Xu,Wei Tao,Jessalyn M. Ubellacker,Michael Lim,Michael Lim,Daniel Aum,Gha Young Lee,Kun Zhou,Harshal Zope,Mi Kyung Yu,Wuji Cao,Wuji Cao,James Trevor Oswald,James Trevor Oswald,Meshkat Dinarvand,Morteza Mahmoudi,Robert Langer,Philip W. Kantoff,Omid C. Farokhzad,Omid C. Farokhzad,Bruce R. Zetter,Jinjun Shi +22 more
TL;DR: It is shown that PTEN messenger RNA can be reintroduced into PTEN-null prostate cancer cells in vitro and in vivo via its encapsulation in polymer–lipid hybrid nanoparticles coated with a polyethylene glycol shell and this work provides proof-of-principle evidence of the restoration of mRNA-based tumour suppression in vivo.
Journal ArticleDOI
Author Correction: Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA
Mohammad Ariful Islam,Yingjie Xu,Wei Tao,Jessalyn M. Ubellacker,Michael Lim,Michael Lim,Daniel Aum,Gha Young Lee,Kun Zhou,Harshal Zope,Mi Kyung Yu,Wuji Cao,Wuji Cao,James Trevor Oswald,James Trevor Oswald,Meshkat Dinarvand,Morteza Mahmoudi,Robert Langer,Philip W. Kantoff,Omid C. Farokhzad,Omid C. Farokhzad,Bruce R. Zetter,Jinjun Shi +22 more
TL;DR: The authors wish to add the following sentence into the ‘Competing interests’ section of this Article: “P.W.K. has investment interest in Context Therapeutic LLC, DRGT, Placon, Seer Biosciences and Tarveda Therapeutics.”