D
Daniel Djakiew
Researcher at Georgetown University
Publications - 52
Citations - 3131
Daniel Djakiew is an academic researcher from Georgetown University. The author has contributed to research in topics: Prostate cancer & Stromal cell. The author has an hindex of 31, co-authored 52 publications receiving 3026 citations. Previous affiliations of Daniel Djakiew include University of Washington & Georgetown University Medical Center.
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Journal ArticleDOI
Human prostate cancer risk factors.
David G. Bostwick,Harry B. Burke,Daniel Djakiew,Susan Y. Euling,Shuk-Mei Ho,Joseph R. Landolph,Howard Morrison,Babasaheb Sonawane,Tiffany Shifflett,David J. Waters,David J. Waters,Barry G. Timms +11 more
TL;DR: The authors conclude that most of the data regarding risk relies, of necessity, on epidemiologic studies, but animal and cell culture models offer promise in confirming some important findings.
Journal Article
Epidermal Growth Factor Promotes MDA-MB-231 Breast Cancer Cell Migration through a Phosphatidylinositol 3′-Kinase and Phospholipase C-dependent Mechanism
TL;DR: This article found that EGF may influence human breast cancer progression via migratory pathways, the signaling for which appears to be dissociated, at least in part, from the proliferative pathways.
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Growth and Characterization of Polarized Monolayers of Epididymal Epithelial Cells and Sertoli Cells in Dual Environment Culture Chambers
TL;DR: Polarized monolayers of epididymal epithelial cells and Sertoli cells can be obtained by growing the cells at high density on extracellular matrix-impregnated permeable supports and maintaining the monol layers in specially constructed culture chambers to develop a permeability barrier.
Journal Article
Regulation of Growth by a Nerve Growth Factor-like Protein Which Modulates Paracrine Interactions between a Neoplastic Epithelial Cell Line and Stromal Cells of the Human Prostate
TL;DR: The results suggest that TSU-pr1 tumor cells and HPS cells secrete NGF-like protein(s) which modulate their paracrine interactive growth in vitro.
Journal Article
Cell cycle-independent death of prostate adenocarcinoma is induced by the trk tyrosine kinase inhibitor CEP-751 (KT6587).
Craig A. Dionne,Anna Marie Camoratto,Jitesh P. Jani,Erling Emerson,Nicola Neff,Jeffry L. Vaught,Chikara Murakata,Daniel Djakiew,John Lamb,Steve Bova,Daniel J. George,John T. Isaacs +11 more
TL;DR: CEP-751 is selective for cancerous versus normal prostate cells and affects the growth of only a limited number of nonprostate tumors, and represents a novel therapeutic approach to the management of both hormone-dependent and hormone-independent prostate cancer.