D
Daniel E. Sturdevant
Researcher at National Institutes of Health
Publications - 90
Citations - 10386
Daniel E. Sturdevant is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Gene & Virulence. The author has an hindex of 46, co-authored 86 publications receiving 9579 citations. Previous affiliations of Daniel E. Sturdevant include Rocky Mountain Laboratories & Government of the United States of America.
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Journal ArticleDOI
Insights into Mechanisms Used by Staphylococcus aureus to Avoid Destruction by Human Neutrophils
Jovanka M. Voyich,Kevin R. Braughton,Daniel E. Sturdevant,Adeline R. Whitney,Battouli Saïd-Salim,Stephen F. Porcella,R. Daniel Long,David W. Dorward,Donald J. Gardner,Barry N. Kreiswirth,James M. Musser,Frank R. DeLeo +11 more
TL;DR: The studies reveal a gene transcription program in a prominent human pathogen that likely contributes to evasion of innate host defense, and induces changes in gene expression not observed in the other strains.
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RNAIII-independent target gene control by the agr quorum-sensing system: insight into the evolution of virulence regulation in Staphylococcus aureus.
Shu Y. Queck,Max Jameson-Lee,Amer E. Villaruz,Thanh-Huy L. Bach,Burhan Khan,Daniel E. Sturdevant,Stacey M. Ricklefs,Min Li,Michael Otto +8 more
TL;DR: It is demonstrated that the Staphylococcus aureus agr quorum-sensing regulon is divided into control of metabolism and PSM cytolysin genes, which occurs independently of the small regulatory RNA RNAIII, and RNAIII-dependent control of additional virulence genes.
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Genomic transcriptional profiling of the developmental cycle of Chlamydia trachomatis.
Robert J. Belland,Guangming Zhong,Deborah D. Crane,Daniel Hogan,Daniel E. Sturdevant,Jyotika Sharma,Wandy L. Beatty,Harlan D. Caldwell +7 more
TL;DR: One immediate early gene (CT147) is a homolog of the human early endosomal antigen-1 that is localized to the chlamydial phagosome; suggesting a functional role for CT147 in establishing the parasitophorous vacuole in a nonfusogenic pathway.
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Evolutionary Genomics of Staphylococcus Aureus: Insights Into the Origin of Methicillin-Resistant Strains and the Toxic Shock Syndrome Epidemic
TL;DR: It is found that lateral gene transfer has played a fundamental role in the evolution of S. aureus, demonstrating that methicillin-resistant strains have evolved multiple independent times, rather than from a single ancestral strain.
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Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks
James C. Smoot,Kent D. Barbian,Jamie J. Van Gompel,Laura M. Smoot,Michael S. Chaussee,Gail L. Sylva,Daniel E. Sturdevant,Stacy M. Ricklefs,Stephen F. Porcella,Larye D. Parkins,Stephen B. Beres,David S. Campbell,Todd M. Smith,Qing Zhang,Vivek Kapur,Judy A. Daly,L. George Veasy,James M. Musser +17 more
TL;DR: DNA microarray analysis of 36 serotype M18 strains from diverse localities showed that most regions of variation were phages or phage-like elements, which provides a critical foundation for accelerated research into ARF pathogenesis and a molecular framework to study the plasticity of GAS genomes.