10.2. Synthesis of Other -Amino Acid Derivatives 3676 10.2.1. Synthesis of -Amino Ketones 3676 10.2.2. Synthesis of -Amino Nitriles 3679 10.2.3. Synthesis of -Amino Phosphinates 3680 10.2.4. Synthesis of -Amino Sulfonates 3681 11. Synthesis of 1,2-Amino Alcohols 3681 11.1. 1,2-Addition to R-Alkoxy Imines 3681 11.2. 1,2-Addition of R-Substituted Organometallic Reagents to N-tert-Butanesulfinyl Imines 3687 * E-mail: jellman@berkeley.edu. † These authors contributed equally to this work. Chem. Rev. 2010, 110, 3600–3740 3600

Synthesis and Applications of tert-Butanesulfinamide

This paper examines the integration of the human and technological aspects of innovation management by modelling the innovation stimulus – innovation capacity relationship in determining innovation performance. The research framework developed in this study was tested amongst 194 managers of Australian firms. The survey responses indicate that both the relationships between innovation stimulus and innovation capacity and between innovation capacity and innovation performance are significant and strong. However, innovation stimulus does not show any direct effect on innovation performance, suggesting that its effect is mediated through innovation capacity. The overall practical implication that can be drawn from the findings is that to achieve high innovation performance, organizations first need to develop the behavioural and cultural context and practices for innovation (i.e. stimulus), and only within such conducive environments is it possible for organizations to develop innovative capacity in research and development and technology so as to more effectively deliver innovation outcomes and performance.

Relationships between innovation stimulus, innovation capacity, and innovation performance

Purpose – Innovation is crucial for attaining a competitive advantage for companies. Innovation, versus imitation, motivates companies to launch new products and become pioneers on markets. Many factors have been shown to be determinants for supporting an organizational innovative orientation. One of them is organizational culture. The objective of this paper is to analyze the organizational culture that fosters or inhibits organizational innovation and imitation strategy.Design/methodology/approach – The paper uses a sample of 471 Spanish companies for examining the hypotheses. Using hierarchical multiple regression analysis, it relates the effect of organizational culture with an innovation strategy.Findings – The results confirm the hypotheses. The paper finds that organizational culture is a clear determinant of innovation strategy. Moreover, adhocracy cultures foster innovation strategies and hierarchical cultures promote imitation cultures.Research limitations/implications – The main limitations are...

Innovation or imitation? The role of organizational culture

https://isiarticles.com/bundles/Article/pre/pdf/4012.pdf

The HR system, organizational culture, and product innovation

https://isiarticles.com/bundles/Article/pre/pdf/4252.pdf

TQM and innovation: a literature review and research framework

https://rua.ua.es/dspace/bitstream/10045/1669/4/Organizational_culture_for_innovation.pdf

Organizational culture for innovation and new technological behavior

This review summarizes recent literature (2000–2015) on the synthesis and pharmaceutical properties of pyrrolopyrimidines. These modified pyrimidine bases, fused to a pyrrole ring, and their corresponding nucleosides display a broad applicability in medicinal chemistry. This overview is divided into three main sections, according to the respective isomers: pyrrolo[2,3-d]pyrimidines, pyrrolo[3,2-d]pyrimidines, and pyrrolo[3,4-d]pyrimidines. Each section contains a description of common retro-synthetic strategies, with particular attention for newly reported synthetic entries to the scaffold. Next, the synthetic strategies and the ways in which the scaffolds can be further modified are exemplified according to the biological properties of the obtained products.

Daniel Garcia

Papers

Organizational culture for innovation and new technological behavior

Synthetic Entries to and Biological Activity of Pyrrolopyrimidines

An unprecedented use for glycerol: chemoselective reducing agent for sulfoxides

Regioselective reductive opening of substituted phthalans: synthetic applications

Reductive Ring‐Opening of Phthalan and Isochroman: Application to the Stereoselective Synthesis of Tetrahydroisoquinolines and Tetrahydrobenzazepines