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Daniel R. Franken
Researcher at Eastern Virginia Medical School
Publications - 7
Citations - 601
Daniel R. Franken is an academic researcher from Eastern Virginia Medical School. The author has contributed to research in topics: Sperm & Zona pellucida. The author has an hindex of 5, co-authored 7 publications receiving 597 citations. Previous affiliations of Daniel R. Franken include University of the Free State & South African Medical Research Council.
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Journal ArticleDOI
The hemizona assay (HZA): development of a diagnostic test for the binding of human spermatozoa to the human hemizona pellucida to predict fertilization potential * † ‡
Lani J. Burkman,Charles C. Coddington,Daniel R. Franken,Thinus F. Kruger,Zev Rosenwaks,Gary D. Hodgen +5 more
TL;DR: Sperm from fertile men exhibited significantly higher binding capacity to hemizonae compared with sperm from men who had fertilization failure during in vitro fertilization (IVF) treatment, demonstrating that the HZA may be a useful diagnostic tool in male infertility evaluations.
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Hemizona assay using salt‐stored human oocytes: Evaluation of zona pellucida capacity for binding human spermatozoa
Daniel R. Franken,Lani J. Burkman,Sergio Oehninger,Charles C. Coddington,Charles C. Coddington,Lucinda L. Veeck,Thinus F. Kruger,Zev Rosenwaks,Gary D. Hodgen +8 more
TL;DR: Salt storage offers a simple and inexpensive means for accumulating and transporting human zonae pellucida; the resulting hemizonae function effectively in the new hemizona assay (HZA) for estimating sperm binding potential.
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The hemizona assay: its role in identifying male factor infertility in assisted reproduction
Daniel R. Franken,Daniel R. Franken,Anibal A. Acosta,Anibal A. Acosta,Thinus F. Kruger,Thinus F. Kruger,Carl J. Lombard,Carl J. Lombard,Sergio Oehninger,Sergio Oehninger,Gary D. Hodgen,Gary D. Hodgen +11 more
TL;DR: The results indicated the HZA and HZI contribute important information and can serve in conjunction with other semen characteristics as useful tools during the diagnosis of the male factor in assisted reproduction.
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Human preovulatory oocytes have a higher sperm-binding ability than immature oocytes under hemizona assay conditions: evidence supporting the concept of "zona maturation".
Sergio Oehninger,Lucinda L. Veeck,Daniel R. Franken,Thinus F. Kruger,Anibal A. Acosta,Gary D. Hodgen +5 more
TL;DR: Full meiotic competence of human oocytes is associated with an increased zona pellucida-binding potential under hemizona assay (HZA) conditions.
Journal ArticleDOI
The hemizona assay (HZA): finding sperm that have the "right stuff".
Gary D. Hodgen,Lani J. Burkman,Charles C. Coddington,Charles C. Coddington,Daniel R. Franken,Daniel R. Franken,Sergio Oehninger,Thinus F. Kruger,Zev Rosenwaks +8 more
TL;DR: This research presents a novel and scalable approach to providing informed consent for vaginal and laparoscopic mesh placement in women with high-risk pregnancies that combines traditional and innovative methods.