D
Daniela Fraccarollo
Researcher at University of Würzburg
Publications - 63
Citations - 3834
Daniela Fraccarollo is an academic researcher from University of Würzburg. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 33, co-authored 59 publications receiving 3539 citations. Previous affiliations of Daniela Fraccarollo include Technische Universität München & Hannover Medical School.
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Journal ArticleDOI
Haeme oxygenase promotes progenitor cell mobilization, neovascularization, and functional recovery after critical hindlimb ischaemia in mice
Jörn Tongers,Julia-Marie Knapp,Mortimer Korf,Tibor Kempf,Anne Limbourg,Florian P. Limbourg,Zhixiong Li,Daniela Fraccarollo,Johann Bauersachs,Xiaoqiang Han,Helmut Drexler,Beate Fiedler,Kai C. Wollert +12 more
TL;DR: It is postulated that haeme oxygenase (HO) is required for progenitor cell recruitment, neovascularization, and blood flow recovery after critical hindlimb ischaemia (HLI) and that HOs are required for functional recovery after HLI.
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Guanylyl cyclase activator ataciguat improves vascular function and reduces platelet activation in heart failure.
TL;DR: Chronic sGC activation improved vasomotor function and reduced platelet activation in CHF rats, and endothelium-dependent, NO-mediated vasorelaxation as well as vascular sensitivity to exogenous NO were significantly impaired in aortic rings fromCHF rats and normalised by ataciguat.
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Time course of right ventricular remodeling in rats with experimental myocardial infarction
Matthias Nahrendorf,Kai Hu,Daniela Fraccarollo,Karl-Heinz Hiller,Axel Haase,Wolfgang R. Bauer,Georg Ertl +6 more
TL;DR: Because RV wall stress was not increased after infarction, mechanical factors may not conclusively explain hypertrophy, which maintained balanced loading conditions for the RV even after large LV infarctions.
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The CX3C Chemokine Fractalkine Induces Vascular Dysfunction by Generation of Superoxide Anions
Andreas Schäfer,Christian Schulz,Daniela Fraccarollo,Piet W.L. Tas,Meike Leutke,Martin Eigenthaler,Stefan Seidl,Peter Heider,Georg Ertl,Steffen Massberg,Johann Bauersachs +10 more
TL;DR: In addition to its role as a chemokine and adhesion molecule, fractalkine induces vascular dysfunction by stimulating vascular reactive oxygen species resulting in reduced NO bioavailability.
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Simvastatin improves left ventricular function after myocardial infarction in hypercholesterolemic rabbits by anti-inflammatory effects
TL;DR: It is suggested that anti-inflammatory and anti-oxidative effects of simvastatin substantially contribute to its beneficial effects on cardiac function after myocardial infarction.