D
Daniela S. S. Lobo
Researcher at Centre for Addiction and Mental Health
Publications - 34
Citations - 1163
Daniela S. S. Lobo is an academic researcher from Centre for Addiction and Mental Health. The author has contributed to research in topics: Major depressive disorder & Amphetamine. The author has an hindex of 16, co-authored 32 publications receiving 1048 citations. Previous affiliations of Daniela S. S. Lobo include University of São Paulo & University of Calgary.
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Journal ArticleDOI
In vivo evidence for greater amphetamine-induced dopamine release in pathological gambling: a positron emission tomography study with [(11)C]-(+)-PHNO.
Isabelle Boileau,Doris Payer,Bindiya Chugani,Daniela S. S. Lobo,Sylvain Houle,Alan A. Wilson,Jerry J. Warsh,Stephen J. Kish,Martin Zack +8 more
TL;DR: The results are consistent with a hyperdopaminergic state in PG, and support the hypothesis that dopaminergic sensitization involving D3-related mechanisms might contribute to the pathophysiology of behavioral addictions.
Journal ArticleDOI
The D2/3 dopamine receptor in pathological gambling: a positron emission tomography study with [11C]-(+)-propyl-hexahydro-naphtho-oxazin and [11C]raclopride.
Isabelle Boileau,Doris Payer,Bindiya Chugani,Daniela S. S. Lobo,A Behzadi,A Behzadi,Pablo Rusjan,Sylvain Houle,Alan A. Wilson,Alan A. Wilson,Jerry J. Warsh,Jerry J. Warsh,Stephen J. Kish,Martin Zack +13 more
TL;DR: There appear to be no marked differences in D2 /D3 levels between healthy subjects and pathological gamblers, suggesting that low receptor availability may not be a necessary feature of addiction, but relationships between [11C]-PHNO binding and gambling severity/impulsiveness suggests involvement of the D3 receptor in impulsive/compulsive behaviours.
Journal ArticleDOI
Factors at play in faster progression for female pathological gamblers: An exploratory analysis
Hermano Tavares,Silvia S. Martins,Daniela S. S. Lobo,Camila Magalhães Silveira,Valentim Gentil,David C. Hodgins +5 more
TL;DR: Two factors could be at play for treatment-seeking female gamblers in Brazil: a potential gender vulnerability and a cultural environment yielding them access to a narrower range of gambling games that includes mainly the most addictive ones.
Journal ArticleDOI
Association of functional variants in the dopamine D2-like receptors with risk for gambling behaviour in healthy Caucasian subjects.
Daniela S. S. Lobo,Daniela S. S. Lobo,Renan P. Souza,Renan P. Souza,Ryan P. Tong,Ryan P. Tong,David M. Casey,David C. Hodgins,Garry J. Smith,Robert J. Williams,Donald Schopflocher,Robert T. Wood,Nady el-Guebaly,James L. Kennedy,James L. Kennedy +14 more
TL;DR: It is found that none of the single polymorphisms investigated on DRD1 and DRD3 were associated with CPGI scores in healthy subjects, and the role of dopamine D2-like receptor in addiction susceptibility is provided.
Journal ArticleDOI
Genetic aspects of pathological gambling: a complex disorder with shared genetic vulnerabilities.
TL;DR: Findings from genetic studies conducted on pathological gambling corroborate further the importance of understanding the biological underpinnings of PG in the development of more specific treatment and prevention strategies.