D
Danièle Bouhours
Researcher at French Institute of Health and Medical Research
Publications - 28
Citations - 530
Danièle Bouhours is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Glycolipid & Small intestine. The author has an hindex of 13, co-authored 28 publications receiving 510 citations. Previous affiliations of Danièle Bouhours include University of Nantes.
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Simultaneous expression by porcine aorta endothelial cells of glycosphingolipids bearing the major epitope for human xenoreactive antibodies (Gal alpha 1-3Gal), blood group H determinant and N-glycolylneuraminic acid.
TL;DR: Porcine endothelial cells differ from human endothelial Cells by expression of glycosphingolipids that are absent in man: two Galα1–3Gal-terminated glycolipids recognized by human natural antibodies, and twoN-glycolylneuraminic acid- terminated gangliosides which are potent immunogens.
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A novel glycosphingolipid expressed in pig kidney: Galα1-3Lewisx hexaglycosylceramide
TL;DR: The characterization of Galα1-3Lex in pig kidney indicates a new epitope capable of recognition by human natural antibodies in the context of xenotransplantation of pig organs to man and adds new members to the family of Lex-based glycolipids.
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Hydroxylation of CMP-NeuAc controls the expression of N-glycolylneuraminic acid in GM3 ganglioside of the small intestine of inbred rats.
TL;DR: It was concluded that the key enzyme responsible for the presence of NeuGc in GM3 is a CMP-NeuAc hydroxylase and that mutant rats carry a defect that is specific to intestine.
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Tissue-specific expression of GM3(NeuGc) and GD3(NeuGc) in epithelial cells of the small intestine of strains of inbred rats. Absence of NeuGc in intestine and presence in kidney gangliosides of brown Norway and spontaneously hypertensive rats.
TL;DR: The analysis of the ganglioside composition of the epithelium of the small intestine of the first generation hybrids of SHR with DA and BN demonstrated that the expressions ofGM3 (NeuGc) and GD3 were genetically transmitted as dominant traits and that BN and SHR were likely to carry the same deficient gene that led to the expression of GM3(NeuAc) instead of GM 3(Neuraminic acid) in theSmall intestine.
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Abnormal fatty acid composition of erythrocyte glycosphingolipids in congenital dyserythropoietic anemia type II.
TL;DR: Glycosphingolipids were isolated from the erythrocytes of three siblings clinically affected with congenital dyserythropoietic anemia type II and contained higher amounts of long chain fatty acids in CDA-II patients than in controls.