D
Darren C. C. Wong
Researcher at University of California, Los Angeles
Publications - 6
Citations - 677
Darren C. C. Wong is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: Resilin & Gene. The author has an hindex of 6, co-authored 6 publications receiving 603 citations. Previous affiliations of Darren C. C. Wong include University of Queensland & Commonwealth Scientific and Industrial Research Organisation.
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Journal ArticleDOI
Synthesis and properties of crosslinked recombinant pro-resilin.
Christopher M. Elvin,Andrew G. Carr,Mickey G. Huson,J. M. Maxwell,Roger Pearson,Tony Vuocolo,N. Liyou,Darren C. C. Wong,Darren C. C. Wong,David J. Merritt,Nicholas E. Dixon +10 more
TL;DR: The cloning and expression of the first exon of the Drosophila CG15920 gene as a soluble protein in Escherichia coli is reported and it is shown that this recombinant protein can be cast into a rubber-like biomaterial by rapid photochemical crosslinking.
Journal ArticleDOI
Design and facile production of recombinant resilin-like polypeptides: gene construction and a rapid protein purification method
Russell E. Lyons,Emmanuelle Lesieur,Mi-Sook Kim,Darren C. C. Wong,Mickey G. Huson,Kate M. Nairn,Alan G. Brownlee,Roger Pearson,Christopher M. Elvin +8 more
TL;DR: A recursive cloning strategy for generating synthetic genes encoding multiple copies of consensus polypeptides, based on the repetitive domains within resilin-like genes from D. melanogaster and Anopheles gambiae are described.
Journal ArticleDOI
Molecular and functional characterisation of resilin across three insect orders.
Russell E. Lyons,Darren C. C. Wong,Mi-Sook Kim,Nicolas Lekieffre,Mickey G. Huson,Tony Vuocolo,David J. Merritt,Kate M. Nairn,Daniel M. Dudek,Michelle L. Colgrave,Christopher M. Elvin +10 more
TL;DR: This study shows that resilin gene and protein sequences are broadly conserved and that crosslinked recombinant resilin proteins share similar mechanical properties from flying to jumping insects.
Expression of the Rubber-Like Protein, Resilin, in Developing and Functional Insect Cuticle Determined Using a Drosophila Anti-Rec 1
TL;DR: For the first time, resilin expression has been detected during embryogenesis, revealing segmental patches of resilin in the developing epidermis of Drosophila.
Journal ArticleDOI
Expression of the rubber-like protein, resilin, in developing and functional insect cuticle determined using a Drosophila anti-rec 1 resilin antibody
TL;DR: In this paper, an antibody to recombinant Drosophila melanogaster pro-resilin was used to examine resilin expression in a wider range of insects, revealing segmental patches of insect resilin in the developing epidermis.