Darrin Lemmer

TL;DR: This study demonstrates how NASP compares with other tools in the analysis of two real bacterial genomics datasets and one simulated dataset and demonstrates differences in results based on the choice of the reference genome and choice of inferring phylogenies from concatenated SNPs or alignments including monomorphic positions.

TL;DR: Preliminary results show a common ST258 ancestor emerged from its diverse parental clonal group around 1995 and likely acquired bla KPC prior to dissemination, helping to better understand the global dissemination of this strain, and identifies genetic markers unique to ST258.

TL;DR: A high-throughput in vitro screening assay to isolate intestinal commensal bacteria with anti-inflammatory capacity from a healthy fecal microbiota transplantation donor found that the Bacteroides strains isolated and characterized have potential to be used as so-called next-generation probiotics.

TL;DR: In vitro findings indicate that O. splanchnicus and its effector molecules transported in OMVs could potentially exert anti-inflammatory action in the gut epithelium, and seems to be a commensal with a primarily beneficial interaction with the host.

TL;DR: The Next Gen-RDST assay was able to estimate the proportion of resistant-to-wild-type alleles down to mixtures of ≤1%, which demonstrates the ability to detect very low levels of resistant variants not detected by pyrosequencing and possibly below the threshold for phenotypic growth methods.