D
Darshan Sapkota
Researcher at Washington University in St. Louis
Publications - 27
Citations - 705
Darshan Sapkota is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Retina & Retinal ganglion. The author has an hindex of 12, co-authored 25 publications receiving 550 citations. Previous affiliations of Darshan Sapkota include Universal College & University at Buffalo.
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Methicillin resistant Staphylococcus aureus: prevalence and antibiogram in a tertiary care hospital in western Nepal.
TL;DR: Given the ability of MRSA to spread from person to person, it is necessary to adhere to rational use of antibiotics and to raise awareness among the concerned communities and tourists who visit this area.
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Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development
TL;DR: It is shown that the onecut transcription factors, Onecut1 and Onecut2, redundantly regulate the formation of all four early-born retinalcell types, namely horizontal cells, ganglion cells, cones, and amacrine cells, and prevent precocious formation of the late retinal cell type, rods.
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High prevalence of multidrug-resistant MRSA in a tertiary care hospital of northern India.
TL;DR: It is concluded that antibiotics other than vancomycin can be used as anti-MRSA agents after a sensitivity test so as to preclude the emergence of resistance to it and that prevailing problems in chemotherapy will escalate unless indiscriminate and irrational usage of antibiotics is checked.
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Onecut 1 and Onecut 2 are potential regulators of mouse retinal development.
TL;DR: Oc1 and Oc2 may regulate the formation of RGCs in a pathway independent of Math5, Pou4f2, and Isl1, as well as function in the genesis and maintenance of HCs.
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Onecut1 is essential for horizontal cell genesis and retinal integrity.
Fuguo Wu,Renzhong Li,Yumiko Umino,Tadeusz J. Kaczynski,Darshan Sapkota,Shengguo Li,Mengqing Xiang,Steven J. Fliesler,David M. Sherry,Maureen Gannon,Eduardo Solessio,Xiuqian Mu +11 more
TL;DR: It is shown that the majority (∼80%) of HCs fail to form during early retinal development, implying that Oc1 is essential for HC genesis, and that HCs are essential for photoreceptor viability, retinal integrity, and normal visual function.