D
Darya A. Meshalkina
Researcher at Saint Petersburg State University
Publications - 31
Citations - 910
Darya A. Meshalkina is an academic researcher from Saint Petersburg State University. The author has contributed to research in topics: Zebrafish & Slow-wave sleep. The author has an hindex of 15, co-authored 28 publications receiving 663 citations. Previous affiliations of Darya A. Meshalkina include Russian Academy of Sciences.
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Journal ArticleDOI
Comparative Analyses of Zebrafish Anxiety-Like Behavior Using Conflict-Based Novelty Tests.
Elana V. Kysil,Darya A. Meshalkina,Erin E. Frick,David J. Echevarria,Denis B. Rosemberg,Caio Maximino,Monica Gomes Lima,Murilo S. de Abreu,Ana C.V.V. Giacomini,Leonardo José Gil Barcellos,Leonardo José Gil Barcellos,Cai Song,Cai Song,Allan V. Kalueff +13 more
TL;DR: This study reappraises NTT and LDT for studying anxiety-like states in zebrafish, and emphasizes their developing utility for neurobehavioral research, which can help optimize drug screening procedures by choosing more appropriate models for testing anxiolytic or anxiogenic drugs.
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Zebrafish Models in NeuroPsychopharmacology and CNS Drug Discovery
Kanza M. Khan,Adam D. Collier,Darya A. Meshalkina,Elana V. Kysil,Sergey L. Khatsko,Tatyana O. Kolesnikova,Yury Yu. Morzherin,Jason E. Warnick,Allan V. Kalueff,David J. Echevarria +9 more
TL;DR: Recent developments in zebrafish genetics and small molecule screening are summarized, which markedly enhance the disease modelling and the discovery of novel drug targets.
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Modeling consequences of prolonged strong unpredictable stress in zebrafish: Complex effects on behavior and physiology
Cai Song,Cai Song,Bai-Ping Liu,Yongping Zhang,Zhilan Peng,JiaJia Wang,Adam D. Collier,David J. Echevarria,Katerina V. Savelieva,Robert F. Lawrence,Christopher S. Rex,Darya A. Meshalkina,Allan V. Kalueff +12 more
TL;DR: These findings support zebrafish as a useful in‐vivo model of chronic stress, also calling for further cross‐species studies of both shared/overlapping and distinct neurobiological responses to chronic stress.
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Animal inflammation-based models of depression and their application to drug discovery.
Li Ma,Konstantin A. Demin,Tatyana O. Kolesnikova,Sergey L. Khatsko,Xiaokang Zhu,Xiaodong Yuan,Cai Song,Darya A. Meshalkina,Brian E. Leonard,Li Tian,Li Tian,Allan V. Kalueff +11 more
TL;DR: It is suggested that novel antidepressants can be developed based on targeting microglia-, PUFAs-, glucocorticoid- and gut microbiota-mediated cellular pathways, and a wider application of novel model organisms, such as zebrafish, in studying shared, evolutionarily conserved neuro-immune mechanisms of depression.
Journal ArticleDOI
Adult zebrafish in CNS disease modeling: a tank that's half-full, not half-empty, and still filling.
TL;DR: Recent findings using zebrafish CNS assays are summarized, model limitations and the existing challenges are discussed, as well as future directions of research in this field are outlined.