D
David Burke
Researcher at Royal Prince Alfred Hospital
Publications - 408
Citations - 26730
David Burke is an academic researcher from Royal Prince Alfred Hospital. The author has contributed to research in topics: Reflex & Muscle spindle. The author has an hindex of 89, co-authored 395 publications receiving 24952 citations. Previous affiliations of David Burke include Elsevier & Ege University.
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Book ChapterDOI
The Human Muscle Spindle and its Fusimotor Control
David Burke,Simon C. Gandevia +1 more
TL;DR: It is now 25 years since Hagbarth and Vallbo (1968) described the technique of microneurography, with the first direct recordings of the activity of muscle afferents in human subjects, to take stock of what has been learnt about fusimotor control of human muscle spindles since then.
Journal ArticleDOI
Segmental motoneuronal dysfunction is a feature of amyotrophic lateral sclerosis.
Neil G. Simon,Cindy S.-Y. Lin,Michael Lee,James Howells,Steve Vucic,David Burke,Matthew C. Kiernan,Matthew C. Kiernan +7 more
TL;DR: Changes in the slope ratio (Hθ/Mθ) in ALS suggested that alterations in peripheral motor nerve excitability following UMN damage may affect the recorded H-reflex, and further insight is provided into the pathophysiology of ALS.
Journal ArticleDOI
Larval Environment Alters Amphibian Immune Defenses Differentially across Life Stages and Populations
TL;DR: The work suggests that the susceptibility of amphibians to emerging diseases could be related to variability in the larval environment and calls for research into the relative influence of potentially less benign anthropogenic environmental changes on innate immune defense traits.
Journal ArticleDOI
Component of muscle spindle discharge related to arterial pulse
B. McKeon,David Burke +1 more
TL;DR: The arterial pulse can be significant contributor to the variability of muscle spindle discharge and the pulsatile effects seen in the responses of single afferents are unlikely to be eliminated in the summed activity forming the population response.
Journal ArticleDOI
Abnormalities of axonal excitability are not generalized in early multifocal motor neuropathy.
Cecilia Cappelen-Smith,Satoshi Kuwabara,Cindy S.-Y. Lin,Cindy S.-Y. Lin,David Burke,David Burke +5 more
TL;DR: This study provides no evidence for a generalized subclinical abnormality in MMN, at least when disease duration is less than 6 years, and indices of axonal excitability were similar to those in controls.