D
David Dunkin
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 39
Citations - 752
David Dunkin is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Inflammatory bowel disease. The author has an hindex of 11, co-authored 27 publications receiving 522 citations.
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Journal ArticleDOI
Skin exposure promotes a Th2-dependent sensitization to peanut allergens
Leticia Tordesillas,Ritobrata Goswami,Sara Benedé,Galina Grishina,David Dunkin,Kirsi M. Järvinen,Soheila J. Maleki,Hugh A. Sampson,M. Cecilia Berin +8 more
TL;DR: The hypothesis that peanuts are allergenic due to inherent adjuvant activity is supported and it is suggested that skin exposure to food allergens contributes to sensitization to foods in early life.
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Real World Experience With Ustekinumab in Children and Young Adults at a Tertiary Care Pediatric Inflammatory Bowel Disease Center.
Judy R Dayan,Michael T. Dolinger,Keith J. Benkov,David Dunkin,Jacqueline Jossen,Joanne Lai,Becky L. Phan,Nanci Pittman,Marla Dubinsky +8 more
TL;DR: The results suggest that ustekinumab is efficacious and safe in pediatric patients with IBD and controlled clinical trial data are needed to confirm these observations.
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Allergic sensitization can be induced via multiple physiologic routes in an adjuvant-dependent manner.
TL;DR: The skin is a potent and likely important physiologic route of sensitization whereby adjuvant induces an efflux of antigen-bearing dermal dendritic cells to the lymph node that generate a proallergic T(H)2 response.
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EBV Status and Thiopurine Use in Pediatric IBD.
Julia Gordon,Archana Ramaswami,Marc Beuttler,Jacqueline Jossen,Nanci Pittman,Joanne Lai,David Dunkin,Keith J. Benkov,Marla Dubinsky +8 more
TL;DR: EBV status may be an important determinate of whether physicians prescribe thiopurines given the risk of primary EBV infections and lymphoproliferative diseases.
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Ganoderic acid C1 isolated from the anti-asthma formula, ASHMI™ suppresses TNF-α production by mouse macrophages and peripheral blood mononuclear cells from asthma patients.
Changda Liu,Nan Yang,Ying Song,Li Xin Wang,Jiachen Zi,Shuwei Zhang,David Dunkin,Paula J. Busse,David Weir,Jody Tversky,Rachel L. Miller,Joseph Goldfarb,Jixun Zhan,Xiu-Min Li +13 more
TL;DR: It is reported that G. uralensis inhibited TNF-α production by murine macrophages; and that the methylene chloride (MC)-triterpenoid-enriched fraction, but not the polysaccharide-en enriched fraction, contained the inhibitory compounds.